{"id":"W1993727333","doi":"10.1038/ncomms7741","title":"Global analysis of fungal morphology exposes mechanisms of host cell escape","year":2015,"lang":"en","type":"article","venue":"Nature Communications","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":243,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Genome Canada","keywords":"Biology; Candida albicans; Virulence; Pyroptosis; Cell biology; Microbiology; Multicellular organism; Corpus albicans; Cryptococcus neoformans; Immune system; Macrophage; Phagosome; Morphogenesis; Filamentation; Cell; Programmed cell death; Phagocytosis; Genetics; Gene; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001036382,0.0001881076,0.0001912779,0.0003847295,0.0001544078,0.0005058108,0.0001461701,0.0002268529,0.0007015517],"category_scores_gemma":[0.0001429359,0.0001284274,0.0001806286,0.0002860391,0.0002501698,0.0001937744,0.0002878518,0.0004372488,0.0001735701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002832124,"about_ca_system_score_gemma":0.0001509305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005225017,"about_ca_topic_score_gemma":0.001133601,"domain_scores_codex":[0.9999042,0.000008927477,0.000003903896,0.00002627314,0.00003284319,0.00002382657],"domain_scores_gemma":[0.9998702,0.00002661395,0.00003676044,0.00002599442,0.00001503542,0.00002545928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004218723,0.000004087841,0.001725148,0.00001334599,0.000003177772,0.00002226119,0.00001387906,0.00009569532,0.9954253,0.000104903,0.00001907287,0.002530853],"study_design_scores_gemma":[0.000006150399,0.0001320067,0.1551417,0.000009785811,0.00002335853,0.0004772782,0.0001147853,0.003058269,0.8389658,0.0003463152,0.001711477,0.0000130316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864855,0.0007302655,0.0102096,0.00005073102,0.000007191971,0.00001302201,0.0005992047,0.000187169,0.001717248],"genre_scores_gemma":[0.9949051,0.0004283694,0.003404905,0.00003966035,0.000003462559,0.00001466791,0.0003723076,0.00003956134,0.0007920233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007015517,"threshold_uncertainty_score":0.002346933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03520152267915348,"score_gpt":0.3386322628498982,"score_spread":0.3034307401707447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}