{"id":"W1993806283","doi":"10.1006/jmcc.2000.1315","title":"Depresssed Responsiveness of Phospholipase C Isoenzymes to Phosphatidic Acid in Congestive Heart Failure","year":2001,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Phosphatidic acid; PLD2; Phospholipase D; Phospholipase; Internal medicine; Heart failure; Endocrinology; Phospholipase C; Phospholipase A2; Isozyme; Biochemistry; Chemistry; Biology; Medicine; Signal transduction; Enzyme; Phospholipid; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005266739,0.0001547037,0.000450327,0.0001588299,0.00002873272,0.000008893792,0.0001311525,0.0001798672,0.00001091403],"category_scores_gemma":[0.0002184212,0.000145371,0.0001876375,0.000166395,0.00009550887,0.000006861696,0.00007411392,0.0001378564,8.926995e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001381229,"about_ca_system_score_gemma":0.0001057324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001047983,"about_ca_topic_score_gemma":0.000005410566,"domain_scores_codex":[0.9987091,0.0002924646,0.0004202767,0.0002217909,0.0001454672,0.0002109139],"domain_scores_gemma":[0.9992064,0.00002094387,0.0001879989,0.0002067042,0.0002364139,0.0001415117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008450914,0.00002630216,0.006653119,0.00001567269,0.00008654869,0.0004029047,0.00004943763,0.002105238,0.9890256,0.00009216143,0.0001780798,0.000519841],"study_design_scores_gemma":[0.001189179,0.0005716635,0.003060932,0.00005827446,0.0000412997,0.0005586261,0.0001460397,0.00001580514,0.9818333,0.000132806,0.01224271,0.0001493051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9618053,0.01582856,0.02169224,0.0003726214,0.00007998913,0.0001677562,0.000005565781,0.000002136127,0.00004584052],"genre_scores_gemma":[0.9979684,0.0002003169,0.00139521,0.0002975441,0.00008698618,0.000007030551,0.00001012457,0.00001640994,0.00001791842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03616317,"threshold_uncertainty_score":0.5928059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006980699535074185,"score_gpt":0.2319607470376624,"score_spread":0.2249800475025882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}