{"id":"W1993860951","doi":"10.1371/journal.pbio.1001250","title":"The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres","year":2012,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; National Institutes of Health; Cancer Research UK; Wellcome Trust; National Institute of General Medical Sciences; Wellcome","keywords":"Aurora B kinase; Kinetochore; Cell biology; Biology; Centromere; Aurora inhibitor; Spindle checkpoint; Aurora kinase; Chromosome segregation; Polo-like kinase; Spindle apparatus; Genetics; Cell cycle; Cell division; Chromosome; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006290498,0.0003278202,0.0001153631,0.0001395563,0.0001843221,0.0003213367,0.0001072555,0.0001437352,0.001528751],"category_scores_gemma":[0.000119782,0.0001309522,0.0001644081,0.00008702104,0.0001400551,0.0002255056,0.0002878365,0.0002686675,0.0004306347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004858574,"about_ca_system_score_gemma":0.0002431023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008938722,"about_ca_topic_score_gemma":0.001524557,"domain_scores_codex":[0.9999119,0.000005748966,0.000004128577,0.00003337099,0.00002332529,0.00002148614],"domain_scores_gemma":[0.9999357,0.000006863781,0.00001795116,0.000008576592,0.000009715931,0.00002102597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006433706,0.000005815293,0.0005661569,0.00001983493,0.000002105224,0.00007060304,0.00001291819,0.00003217624,0.9982336,0.0001451428,0.00002783183,0.0008194112],"study_design_scores_gemma":[0.00001736214,0.00009237813,0.0232434,0.00000741369,0.00001019052,0.0005292253,0.00003601834,0.001186858,0.9684933,0.0001063666,0.006272476,0.000004991938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923279,0.001815038,0.002331058,0.00005896372,0.00002630094,0.00001428225,0.0002135016,0.0000971593,0.003115891],"genre_scores_gemma":[0.9954467,0.0005109641,0.0005306879,0.00001886522,0.000005434567,0.000007589634,0.0003204466,0.00001142677,0.003147851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001528751,"threshold_uncertainty_score":0.005114138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0181324923900999,"score_gpt":0.25310844963229,"score_spread":0.2349759572421901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}