{"id":"W1993936359","doi":"10.1128/jb.182.19.5620-5623.2000","title":"Mutation of the Lipopolysaccharide Core Glycosyltransferase Encoded by <i>waaG</i> Destabilizes the Outer Membrane of <i>Escherichia coli</i> by Interfering with Core Phosphorylation","year":2000,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences; University of Guelph","funders":"","keywords":"Bacterial outer membrane; Heptose; Biology; Escherichia coli; Phosphorylation; Lipopolysaccharide; Mutant; Mutation; Glucosyltransferase; Biochemistry; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001166569,0.0005715104,0.0002001833,0.0001858022,0.000179653,0.0003679075,0.0003519082,0.0002958736,0.0007529226],"category_scores_gemma":[0.0002212425,0.0002000175,0.0002845025,0.0001673329,0.0003868299,0.0001590527,0.0003556103,0.0006641251,0.000551875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000316129,"about_ca_system_score_gemma":0.0001896004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009618693,"about_ca_topic_score_gemma":0.0007555247,"domain_scores_codex":[0.9998487,0.00002786894,0.00002516577,0.00002567167,0.0000403364,0.00003227746],"domain_scores_gemma":[0.9997072,0.00005570993,0.000105639,0.00005207266,0.00002449925,0.00005488432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004978002,0.00002034111,0.0001019097,0.000009148105,0.000003786932,0.00004770153,0.000008926769,0.00006130462,0.9991585,0.0001138694,0.00001793221,0.0004068429],"study_design_scores_gemma":[0.000006651418,0.00008616177,0.001480247,0.000003469671,0.000007591131,0.0001806453,0.00001862484,0.0007031374,0.9968261,0.00004187289,0.0006407474,0.000004737985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995414,0.0001046834,0.003266122,0.00005860359,0.00002248993,0.00002387069,0.0002199518,0.00009825614,0.0007919656],"genre_scores_gemma":[0.9957775,0.0000893257,0.002652028,0.00004361129,0.000005814222,0.00001718151,0.0003564662,0.00006142744,0.0009967075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009618693,"threshold_uncertainty_score":0.002518773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007250815406857123,"score_gpt":0.2103455275561833,"score_spread":0.2030947121493261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}