{"id":"W1993936359","doi":"10.1128/jb.182.19.5620-5623.2000","title":"Mutation of the Lipopolysaccharide Core Glycosyltransferase Encoded by <i>waaG</i> Destabilizes the Outer Membrane of <i>Escherichia coli</i> by Interfering with Core Phosphorylation","year":2000,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences; University of Guelph","funders":"","keywords":"Bacterial outer membrane; Heptose; Biology; Escherichia coli; Phosphorylation; Lipopolysaccharide; Mutant; Mutation; Glucosyltransferase; Biochemistry; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002379307,0.0001747392,0.0003365293,0.0000269407,0.00005623403,0.0000105195,0.0004017991,0.0002609449,0.00007106427],"category_scores_gemma":[0.00003391377,0.00009928441,0.0001206025,0.0001160312,0.0003998882,0.000009042178,0.00004190164,0.0002226908,5.126147e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001399233,"about_ca_system_score_gemma":0.0001038211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000475355,"about_ca_topic_score_gemma":0.00005966429,"domain_scores_codex":[0.9988277,0.0001010867,0.0005951515,0.0001736938,0.0001200571,0.0001823201],"domain_scores_gemma":[0.9989231,0.0000371358,0.0004974229,0.0002880365,0.0002116666,0.00004268318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001300898,0.00006883588,0.0009591593,0.00001998974,0.0001252012,0.000001689261,0.000133694,0.0000614151,0.9950674,0.0000123061,0.0002522612,0.001997179],"study_design_scores_gemma":[0.0008735489,0.001572225,0.0008854482,0.00003971745,0.00008701163,0.0001366788,0.00009808501,0.00002893964,0.9921412,0.00003325189,0.003990897,0.0001130067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982033,0.0004556731,0.0003779822,0.0004528728,0.000210833,0.0001876254,0.00007631165,0.000003232138,0.00003220653],"genre_scores_gemma":[0.9985266,0.0007554494,0.0002742619,0.0002564687,0.00007327086,0.000005082005,0.0000323746,0.00001917379,0.00005737477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003738636,"threshold_uncertainty_score":0.4048701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007250815406857123,"score_gpt":0.2103455275561833,"score_spread":0.2030947121493261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}