{"id":"W1993984639","doi":"10.1111/j.1523-1755.2004.00795.x","title":"Activation of mesangial cell MAPK in responseto homocysteine","year":2004,"lang":"en","type":"article","venue":"Kidney International","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; McMaster University","funders":"","keywords":"Mesangial cell; Endoplasmic reticulum; MAPK/ERK pathway; Unfolded protein response; Internal medicine; Endocrinology; Cell growth; Biology; Cell biology; Chemistry; Signal transduction; Kidney; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002805066,0.0004939078,0.0003021458,0.0004877504,0.0004169511,0.0003431963,0.0002730487,0.0004818501,0.004977025],"category_scores_gemma":[0.0002411233,0.000282751,0.0004826482,0.0002525732,0.0003116802,0.0004919075,0.0003172846,0.0009320905,0.0008732732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004479258,"about_ca_system_score_gemma":0.0003583676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001065451,"about_ca_topic_score_gemma":0.001349118,"domain_scores_codex":[0.9997659,0.00005027445,0.0000136603,0.00002677491,0.00004346312,0.00009980662],"domain_scores_gemma":[0.9998376,0.00002762318,0.0000202784,0.00002507843,0.00002550049,0.00006382625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002938214,0.0001601264,0.0007439387,0.0001501022,0.00002650379,0.0002550059,0.0001241353,0.00007690342,0.9915912,0.0002852969,0.0003830588,0.003265515],"study_design_scores_gemma":[0.0002690543,0.0007679197,0.05096082,0.00003308726,0.00007448687,0.0009412571,0.0005228634,0.001622014,0.9391167,0.000675857,0.004992343,0.00002365901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900712,0.002658482,0.001632277,0.0007175375,0.0001181944,0.00004273009,0.0007006659,0.00007208328,0.003986856],"genre_scores_gemma":[0.9901974,0.001456578,0.001803027,0.0001249296,0.00004904544,0.00008712364,0.0008182921,0.00001251331,0.005451079],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004977025,"threshold_uncertainty_score":0.01664978,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01481432728009412,"score_gpt":0.3053389562467616,"score_spread":0.2905246289666675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}