{"id":"W1994033087","doi":"10.1002/chin.201221165","title":"ChemInform Abstract: Polycyclic Quinolones. Part 2. Synthesis of Novel 4‐Oxo‐1,4‐dihydrobenzo[h][1,3]thiazeto[3,2‐a]quinoline Carboxylic Acids via Oxidative Cyclization of the Corresponding 2‐Mercaptoquinoline Precursors.","year":2012,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Chemistry; Quinoline; Iodine; Vicinal; Iodide; Carbon skeleton; Combinatorial chemistry; Medicinal chemistry; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007441545,0.0004975704,0.0007516252,0.0001332853,0.0001399519,0.00002316588,0.0007604319,0.000559423,0.00210363],"category_scores_gemma":[0.001808413,0.0003538583,0.0003957231,0.0005912287,0.0004078217,0.0005201426,0.0002705001,0.0003548886,0.00002254059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000224505,"about_ca_system_score_gemma":0.0001116092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006796123,"about_ca_topic_score_gemma":0.00001170083,"domain_scores_codex":[0.9967258,0.000001389649,0.001424832,0.0003542686,0.0007482621,0.0007454758],"domain_scores_gemma":[0.9965923,0.0005675919,0.00156804,0.0008483928,0.0002238385,0.0001998577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000244857,0.0005986347,0.0035503,0.0004015254,0.0001744217,1.92284e-7,0.001388863,0.000005389718,0.7470612,0.000133113,0.0005107214,0.2459308],"study_design_scores_gemma":[0.000565275,0.0000293454,0.0117165,0.0003915072,0.0001930283,0.00001391335,0.0005046215,0.0002087342,0.981333,0.00001919236,0.004611865,0.0004129868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8141554,0.0005724066,0.000006028723,0.0001366689,0.0003286394,0.0003370136,0.0001584805,0.0000958548,0.1842095],"genre_scores_gemma":[0.9970692,0.0002121153,0.00007445402,0.00008216858,0.0004140234,0.0001053557,0.000164246,0.00004331719,0.001835161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2455178,"threshold_uncertainty_score":0.9998913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03455586044313488,"score_gpt":0.2660226312292689,"score_spread":0.2314667707861341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}