{"id":"W1994033087","doi":"10.1002/chin.201221165","title":"ChemInform Abstract: Polycyclic Quinolones. Part 2. Synthesis of Novel 4‐Oxo‐1,4‐dihydrobenzo[h][1,3]thiazeto[3,2‐a]quinoline Carboxylic Acids via Oxidative Cyclization of the Corresponding 2‐Mercaptoquinoline Precursors.","year":2012,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Chemistry; Quinoline; Iodine; Vicinal; Iodide; Carbon skeleton; Combinatorial chemistry; Medicinal chemistry; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008721268,0.0003924974,0.0001162615,0.000300238,0.0001443483,0.0001740106,0.0001871353,0.0001845634,0.0107847],"category_scores_gemma":[0.00009318218,0.0001017356,0.0001328794,0.0002179081,0.0001540945,0.0001527501,0.0001373356,0.000234583,0.002187779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002797161,"about_ca_system_score_gemma":0.0003306129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008962397,"about_ca_topic_score_gemma":0.002448673,"domain_scores_codex":[0.9999456,0.00000821952,0.000003166904,0.00001038001,0.00002095114,0.00001158535],"domain_scores_gemma":[0.9999585,0.000004814102,0.000008719408,0.000004220365,0.00001040307,0.00001339634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003080147,0.00006188265,0.0001795062,0.0002313392,0.00001071871,0.0001221555,0.00002846516,0.0003343842,0.9757621,0.0006708415,0.0007574687,0.02153316],"study_design_scores_gemma":[0.0001206834,0.0008562328,0.002336508,0.00001982891,0.00002444246,0.0004002728,0.00001430873,0.0002651338,0.9614995,0.00009878477,0.03435501,0.000009315265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8515465,0.0242994,0.0326422,0.001062612,0.0003615714,0.0008326905,0.009442808,0.001018651,0.07879352],"genre_scores_gemma":[0.9358281,0.01006072,0.0141979,0.0002673044,0.00005780411,0.0001382372,0.004316082,0.00006019113,0.03507372],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0107847,"threshold_uncertainty_score":0.03607839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03455586044313488,"score_gpt":0.2660226312292689,"score_spread":0.2314667707861341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}