{"id":"W1994090690","doi":"10.1016/j.cub.2012.08.039","title":"RNA Interference: Systemic RNAi SIDes with Endosomes","year":2012,"lang":"en","type":"letter","venue":"Current Biology","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"RNA interference; Endosome; Biology; Caenorhabditis elegans; Gene silencing; Cell biology; RNA silencing; Interference (communication); Small interfering RNA; RNA; Genetics; Intracellular; Gene; Computer science; Telecommunications","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001190359,0.0006307951,0.0005853443,0.000307512,0.0006617255,0.001194459,0.0006555804,0.006623134,0.003047072],"category_scores_gemma":[0.002881933,0.0002917804,0.0005099016,0.0001860678,0.001246916,0.0013055,0.0005645192,0.006955188,0.002523577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001097626,"about_ca_system_score_gemma":0.0003972078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003414711,"about_ca_topic_score_gemma":0.0006017312,"domain_scores_codex":[0.999487,0.00009832998,0.00004910344,0.00009398878,0.0002046496,0.00006688196],"domain_scores_gemma":[0.9991245,0.0004865156,0.00008941643,0.00009397781,0.00009835611,0.0001072282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00163429,0.0001797033,0.001539803,0.000369125,0.00010241,0.01030178,0.0001526031,0.0004778183,0.0852045,0.04017554,0.7352376,0.1246249],"study_design_scores_gemma":[0.001056122,0.0005078274,0.004212244,0.0001930546,0.0001703709,0.01401287,0.0002403391,0.00506823,0.1021796,0.04897765,0.8232677,0.0001139927],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.02183846,0.02304922,0.01237695,0.8769867,0.04404209,0.00009500363,0.0003409709,0.0008818387,0.02038864],"genre_scores_gemma":[0.2373903,0.03417926,0.01138337,0.5703671,0.07092784,0.0003141689,0.0003281835,0.0003085878,0.07480109],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.006623134,"threshold_uncertainty_score":0.01019347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02395636398067442,"score_gpt":0.2636536403984984,"score_spread":0.239697276417824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}