{"id":"W1994091090","doi":"10.1038/jcbfm.2014.226","title":"Simvastatin Restored Vascular Reactivity, Endothelial Function and Reduced String Vessel Pathology in a Mouse Model of Cerebrovascular Disease","year":2015,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Neurological Disease Mechanisms and Treatments","field":"Neuroscience","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Gladstone Institutes","keywords":"Simvastatin; Medicine; Vascular disease; Pathology; Cardiology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002346993,0.0005633082,0.0008262364,0.0006683837,0.0002453697,0.0002747966,0.0004630282,0.0005932941,0.001169704],"category_scores_gemma":[0.0001857324,0.0002081584,0.0003524201,0.0002757667,0.0003386326,0.0003934402,0.0001884773,0.001132867,0.0002581531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003446412,"about_ca_system_score_gemma":0.0004678834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001151248,"about_ca_topic_score_gemma":0.001800599,"domain_scores_codex":[0.9998168,0.0000331245,0.00002472764,0.00003002332,0.00003165332,0.00006365156],"domain_scores_gemma":[0.9998068,0.00001398935,0.00005162535,0.00001985036,0.00003277357,0.00007494993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003104432,0.0003939579,0.0003515618,0.00009212398,0.00003891767,0.0001311351,0.00003772739,0.0001132003,0.9915335,0.0001824168,0.0001442854,0.003876921],"study_design_scores_gemma":[0.0004815291,0.00641088,0.01172551,0.00002389301,0.0001413111,0.0003278733,0.00009831529,0.002262177,0.9751785,0.0003432346,0.002980908,0.00002586061],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945985,0.0013118,0.002319571,0.00020848,0.00006919473,0.00004673086,0.0004825388,0.0002630884,0.0007001535],"genre_scores_gemma":[0.9915788,0.001988085,0.002347012,0.0001201197,0.00003788911,0.0001206166,0.0007480322,0.0000476903,0.003011593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001169704,"threshold_uncertainty_score":0.003913045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03730315194091719,"score_gpt":0.2468442426681241,"score_spread":0.2095410907272069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}