{"id":"W1994221786","doi":"10.1039/c2an15881g","title":"Electrochemical detection of hepatitis C viral NS3-4A protease","year":2012,"lang":"en","type":"article","venue":"The Analyst","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Western University","funders":"","keywords":"Protease; Chemistry; NS3; Peptide; Detection limit; Covalent bond; Cleavage (geology); Electrochemistry; Monolayer; Electrode; Biochemistry; Enzyme; Chromatography; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003993263,0.0004331438,0.0003023894,0.0002146864,0.0002039272,0.0003508193,0.0004638008,0.0008289536,0.0006815455],"category_scores_gemma":[0.0004987174,0.0001890549,0.0001739321,0.0001488273,0.0002484254,0.0003620583,0.0003109747,0.0004968806,0.0003561598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002303878,"about_ca_system_score_gemma":0.0001558622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003167094,"about_ca_topic_score_gemma":0.0005513523,"domain_scores_codex":[0.9995787,0.000124743,0.00002171128,0.00007421424,0.0001617628,0.00003883136],"domain_scores_gemma":[0.9998386,0.0000753143,0.00001847417,0.000009697936,0.00004032268,0.00001761531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000255791,0.00001899946,0.000239145,0.00004483581,0.000007924073,0.00003934887,0.00001675779,0.00008701933,0.9949823,0.0001442499,0.00006269482,0.004331066],"study_design_scores_gemma":[0.000007013389,0.0001811542,0.0008698428,0.000006558748,0.00001071186,0.0003001294,0.00003165142,0.004072101,0.9920833,0.0001966426,0.002232515,0.000008320556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7837646,0.01481613,0.1929569,0.00122713,0.0004036904,0.0001567836,0.0003073472,0.0006769465,0.005690434],"genre_scores_gemma":[0.9100779,0.004616505,0.08012771,0.0003652241,0.00007788532,0.00006805333,0.0002058734,0.00002111212,0.004439749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008289536,"threshold_uncertainty_score":0.002279997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005689931910201917,"score_gpt":0.2481913316810209,"score_spread":0.242501399770819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}