{"id":"W1994221786","doi":"10.1039/c2an15881g","title":"Electrochemical detection of hepatitis C viral NS3-4A protease","year":2012,"lang":"en","type":"article","venue":"The Analyst","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Western University","funders":"","keywords":"Protease; Chemistry; NS3; Peptide; Detection limit; Covalent bond; Cleavage (geology); Electrochemistry; Monolayer; Electrode; Biochemistry; Enzyme; Chromatography; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001920589,0.00009080496,0.0001151593,0.00003095509,0.00006007453,0.000005370074,0.0001085141,0.00007754593,0.000002034149],"category_scores_gemma":[0.00004618692,0.00006031392,0.0001276963,0.0001326735,0.00008786283,0.00000364458,0.0000447011,0.00007142916,0.000002058553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001106273,"about_ca_system_score_gemma":0.000009331029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005404193,"about_ca_topic_score_gemma":0.00003275677,"domain_scores_codex":[0.99939,0.00005765812,0.0001497179,0.000123638,0.0000985825,0.0001803972],"domain_scores_gemma":[0.9995031,0.000006155624,0.00009699028,0.0002907139,0.00006096846,0.00004206971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003700253,0.00003664886,0.002507423,0.000003783637,0.0000625926,1.296905e-7,0.000008712363,4.039606e-7,0.9954156,0.00002183089,0.00005781394,0.001848068],"study_design_scores_gemma":[0.00006149428,0.00009309671,0.0008982947,0.000003331186,0.00008089264,0.000009379535,0.00001309306,0.00006850249,0.9964431,0.0000702392,0.002175631,0.00008292407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804593,0.0003575423,0.0187724,0.0000679068,0.00001751051,0.00008754912,0.000003692259,0.0000181255,0.0002160054],"genre_scores_gemma":[0.9984984,0.00009235752,0.000922138,0.00008643461,0.0002328515,0.000008178595,0.000031839,0.000008473956,0.0001192873],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01803918,"threshold_uncertainty_score":0.245953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005689931910201917,"score_gpt":0.2481913316810209,"score_spread":0.242501399770819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}