{"id":"W1994226956","doi":"10.1021/ol061698+","title":"Expanding the Scope of Mn(OAc)<sub>3</sub>-Mediated Cyclizations:  Synthesis of the Tetracyclic Core of Tronocarpine","year":2006,"lang":"en","type":"article","venue":"Organic Letters","topic":"Alkaloids: synthesis and pharmacology","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Acetonitrile; Indole test; Substrate (aquarium); Nitrogen atom; Combinatorial chemistry; Scope (computer science); Core (optical fiber); Medicinal chemistry; Stereochemistry; Ring (chemistry); Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001117849,0.000260052,0.0001460333,0.0001228815,0.0001314061,0.0001827553,0.0002509692,0.0001723902,0.001585863],"category_scores_gemma":[0.0001891717,0.00007435082,0.0001537191,0.000130596,0.000240105,0.0002329365,0.0001990146,0.0003135513,0.0005166695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002040762,"about_ca_system_score_gemma":0.0002413388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005271843,"about_ca_topic_score_gemma":0.0009969572,"domain_scores_codex":[0.9999424,0.000009919406,0.000005684774,0.00001594821,0.000009782846,0.00001617592],"domain_scores_gemma":[0.9999316,0.00001238724,0.00002004117,0.00001330061,0.00001016405,0.00001253706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008429906,0.00001392485,0.00007743754,0.00005114918,0.000004037981,0.0001245544,0.00004441392,0.0001905946,0.9904349,0.0005759026,0.00005390382,0.008344927],"study_design_scores_gemma":[0.000008428933,0.0001498258,0.000536205,0.000004686297,0.000006669959,0.0002183127,0.00001765725,0.0003423409,0.9937033,0.0001468562,0.0048599,0.000005856838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9700381,0.002297341,0.01444594,0.0001743991,0.00004963823,0.0001017985,0.0001851668,0.0002233479,0.01248423],"genre_scores_gemma":[0.989995,0.0009448249,0.006702404,0.00005280083,0.000008466805,0.00003045067,0.0001180027,0.00003311472,0.002114892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001585863,"threshold_uncertainty_score":0.00530529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04036890329457047,"score_gpt":0.3282100816290675,"score_spread":0.287841178334497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}