{"id":"W1994266478","doi":"10.1089/scd.2013.0373","title":"Microenvironmental Regulation of Telomerase Isoforms in Human Embryonic Stem Cells","year":2014,"lang":"en","type":"article","venue":"Stem Cells and Development","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Children's Health Research Institute","keywords":"Telomerase; Biology; Telomerase reverse transcriptase; Telomere; Embryonic stem cell; Molecular biology; Cell biology; Stem cell; Cellular differentiation; Reverse transcriptase; Alternative splicing; Ribonucleoprotein; Gene isoform; RNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003110905,0.0002211086,0.0004118241,0.0001763876,0.0001004164,0.00001514183,0.00007871632,0.000099916,0.00008470439],"category_scores_gemma":[8.846397e-7,0.0001873161,0.00004412108,0.0001284875,0.00009343713,0.00007542481,0.00007020045,0.0001230843,0.0000420675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001366182,"about_ca_system_score_gemma":0.00007201511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003047458,"about_ca_topic_score_gemma":0.00002805668,"domain_scores_codex":[0.9984319,0.00003985646,0.00054068,0.0003671685,0.0002972904,0.000323164],"domain_scores_gemma":[0.9993832,0.00003356756,0.0001577076,0.0002432166,0.00002357877,0.0001587334],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001065068,0.0002821774,0.04108144,0.0005216072,0.00003725759,0.00001414136,0.002271286,0.0000208555,0.8769038,0.00007444694,0.0003165906,0.07836992],"study_design_scores_gemma":[0.001745033,0.0001742712,0.1660881,0.0002184735,0.00001597264,0.00001394041,0.0007201363,0.00006977184,0.8176519,0.00001268339,0.01304462,0.0002451357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984161,0.0003043736,0.0001384832,0.00005376182,0.0001296863,0.0003941872,0.000004708143,0.00002326267,0.0005354033],"genre_scores_gemma":[0.995331,0.000129227,0.001274291,0.0001226083,0.00003270326,0.00001303927,0.000017631,0.0000232905,0.003056233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1250066,"threshold_uncertainty_score":0.7638527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01198983376035632,"score_gpt":0.2143853067634196,"score_spread":0.2023954730030633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}