{"id":"W1994266478","doi":"10.1089/scd.2013.0373","title":"Microenvironmental Regulation of Telomerase Isoforms in Human Embryonic Stem Cells","year":2014,"lang":"en","type":"article","venue":"Stem Cells and Development","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Children's Health Research Institute","keywords":"Telomerase; Biology; Telomerase reverse transcriptase; Telomere; Embryonic stem cell; Molecular biology; Cell biology; Stem cell; Cellular differentiation; Reverse transcriptase; Alternative splicing; Ribonucleoprotein; Gene isoform; RNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001154085,0.0001763543,0.00009853629,0.0001568505,0.0001060705,0.0002695506,0.00007537576,0.00007911012,0.0003696162],"category_scores_gemma":[0.0001157575,0.0001111938,0.0001059569,0.00009481928,0.0001143124,0.0001448581,0.0001905819,0.0001247653,0.0001227826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000136142,"about_ca_system_score_gemma":0.00008996379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000304138,"about_ca_topic_score_gemma":0.0007664888,"domain_scores_codex":[0.9999074,0.00002099436,0.00001233409,0.00002404338,0.00002333765,0.00001190046],"domain_scores_gemma":[0.9999406,0.00001166407,0.00001874019,0.000009865199,0.000009487759,0.000009565775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003758796,0.000003570898,0.0004966691,0.000009500798,0.000001779437,0.00003337571,0.00001618325,0.00004816223,0.9984685,0.00003209946,0.000006531733,0.0008459703],"study_design_scores_gemma":[0.000005830427,0.0001784154,0.0215308,0.00000384513,0.00001174022,0.0002517102,0.00006601074,0.0006398997,0.9753302,0.00008272957,0.001894199,0.000004709284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952499,0.002091821,0.001643327,0.00002445887,0.00001063361,0.000008360896,0.0001213627,0.00002650174,0.0008236546],"genre_scores_gemma":[0.9966519,0.001020078,0.001207114,0.00001543125,0.000007022128,0.00001461715,0.0001804751,0.000009748674,0.0008935624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003696162,"threshold_uncertainty_score":0.001236439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01198983376035632,"score_gpt":0.2143853067634196,"score_spread":0.2023954730030633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}