{"id":"W1994275281","doi":"10.1074/jbc.m112.348227","title":"Characterization of DalS, an ATP-binding Cassette Transporter for d-Alanine, and Its Role in Pathogenesis in Salmonella enterica","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research","keywords":"Salmonella enterica; Regulon; Pathogenicity island; Operon; Biology; Salmonella; Periplasmic space; Effector; Microbiology; Secretion; Type three secretion system; Intracellular; Pathogen; Intracellular parasite; Host (biology); ATP-binding cassette transporter; Cell biology; Virulence; Transporter; Bacteria; Gene; Genetics; Regulation of gene expression; Biochemistry; Mutant; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001119936,0.0001979308,0.0001789814,0.0002333919,0.0000875111,0.0002221392,0.0001092778,0.000183472,0.0002162601],"category_scores_gemma":[0.0002002308,0.00009695052,0.0001984429,0.0001692653,0.0001716141,0.0001384379,0.0001269146,0.0002165866,0.0002032471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003199683,"about_ca_system_score_gemma":0.0002494156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00155779,"about_ca_topic_score_gemma":0.00137922,"domain_scores_codex":[0.9999521,0.000008057325,0.000007383452,0.000008048854,0.00001698587,0.000007521643],"domain_scores_gemma":[0.9998839,0.00001620524,0.00002928424,0.00001091883,0.00002513092,0.00003445686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001073634,0.00002369255,0.001372465,0.00003500891,0.000002838153,0.0001019641,0.0000281919,0.0001298539,0.9966354,0.00008289009,0.0000190683,0.001461171],"study_design_scores_gemma":[0.00003408961,0.0007931296,0.08473416,0.0000198049,0.00003846371,0.001606748,0.0003901225,0.005919475,0.9016854,0.0002542487,0.004503757,0.00002068257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983215,0.0002921477,0.000787146,0.00007730956,0.00000479212,0.000007519683,0.0002456215,0.00001369439,0.0002503077],"genre_scores_gemma":[0.9959883,0.0002144206,0.00178464,0.00002688705,0.000003201147,0.000007295193,0.001267865,0.000006762521,0.0007005928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00155779,"threshold_uncertainty_score":0.003097415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01756792033942122,"score_gpt":0.2483427002014446,"score_spread":0.2307747798620234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}