{"id":"W1994284052","doi":"10.1006/bbrc.2002.6712","title":"Visualization of Sequential Exocytosis in Rat Pancreatic Islet β Cells","year":2002,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Exocytosis; Granule (geology); Islet; Fluorescence microscope; Cell biology; Confocal microscopy; Insulin; Confocal; Chemistry; Biophysics; Membrane; Glipizide; Pancreatic islets; Biology; Biochemistry; Fluorescence; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001606951,0.0002734759,0.0002049021,0.000358934,0.0002305225,0.0005751056,0.000327167,0.000394446,0.001120241],"category_scores_gemma":[0.0001767583,0.0002074627,0.000313464,0.00024143,0.0001686508,0.0006245453,0.0005340437,0.0008424745,0.0004207707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002418159,"about_ca_system_score_gemma":0.0001729399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004519642,"about_ca_topic_score_gemma":0.0004689651,"domain_scores_codex":[0.9999185,0.000008183614,0.000008374919,0.00002060451,0.00001559384,0.00002877502],"domain_scores_gemma":[0.9998004,0.00006320918,0.0000354551,0.00003188187,0.00002285873,0.00004626237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000150095,0.000009601689,0.0001733359,0.00003185195,0.000004324668,0.0001364496,0.00002197253,0.00005767974,0.9971091,0.0004094539,0.00003568921,0.001860476],"study_design_scores_gemma":[0.00004886528,0.0001827238,0.007616288,0.00002185953,0.00002077509,0.001123505,0.0001334599,0.002855334,0.9851029,0.0004224022,0.002460894,0.00001106161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9600959,0.002994879,0.03100377,0.00039481,0.00007925471,0.00004581429,0.0004242681,0.0002276993,0.004733644],"genre_scores_gemma":[0.97122,0.002362289,0.02167848,0.0001352151,0.00004365374,0.00006841888,0.000395328,0.00011642,0.003980082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001120241,"threshold_uncertainty_score":0.003747582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1181056012812387,"score_gpt":0.3805675389381334,"score_spread":0.2624619376568947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}