{"id":"W1994358542","doi":"10.1021/ac801208e","title":"Peptide Biosensors for the Electrochemical Measurement of Protein Kinase Activity","year":2008,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Biochemistry; Casein kinase 2; Kinase; Adenosine triphosphate; Protein kinase A; Combinatorial chemistry; Mitogen-activated protein kinase kinase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002105842,0.0001653214,0.000200352,0.00001214384,0.000107068,0.000005558395,0.0001894647,0.0001618585,0.000003582976],"category_scores_gemma":[0.000464636,0.0001163647,0.000267052,0.0001191766,0.0003121078,0.000002121913,0.00005691943,0.000122224,5.530574e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003068549,"about_ca_system_score_gemma":0.00008340611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005939239,"about_ca_topic_score_gemma":0.000002249632,"domain_scores_codex":[0.9989352,0.00001706265,0.0002059258,0.0003280896,0.0002631417,0.0002506277],"domain_scores_gemma":[0.9991117,0.00002798027,0.0001003405,0.0004198817,0.0002653178,0.00007478489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001655798,0.000102975,0.0001027833,0.00003223755,0.0001155814,0.000001567115,0.000002057656,0.000001076647,0.9983921,0.00000950076,0.0007013039,0.0003732254],"study_design_scores_gemma":[0.0002121659,0.00008720229,0.0001257148,0.00001412621,0.00007365683,0.00001583949,0.00001045232,0.0003371249,0.9941313,0.00003899295,0.00480113,0.0001522543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868159,0.0002195702,0.01163062,0.00043578,0.000006798879,0.000224843,0.0000130702,0.00002577617,0.0006276474],"genre_scores_gemma":[0.9970458,0.00006672232,0.001817546,0.00004972416,0.0001542221,0.00002628325,0.00001960594,0.0000149555,0.0008052133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01022984,"threshold_uncertainty_score":0.4745214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02182015181101446,"score_gpt":0.2682640652026113,"score_spread":0.2464439133915969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}