{"id":"W1994358542","doi":"10.1021/ac801208e","title":"Peptide Biosensors for the Electrochemical Measurement of Protein Kinase Activity","year":2008,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Biochemistry; Casein kinase 2; Kinase; Adenosine triphosphate; Protein kinase A; Combinatorial chemistry; Mitogen-activated protein kinase kinase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001135941,0.00112727,0.0007603959,0.00053665,0.0001911032,0.0006107396,0.001676508,0.001869812,0.001528795],"category_scores_gemma":[0.001389686,0.0005623748,0.0003993655,0.0006347005,0.0003382009,0.0008347923,0.0006011137,0.002144688,0.001395889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005568455,"about_ca_system_score_gemma":0.0002188401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002352179,"about_ca_topic_score_gemma":0.0003674063,"domain_scores_codex":[0.99834,0.000360697,0.00008700768,0.0003854863,0.000706164,0.0001205558],"domain_scores_gemma":[0.9995517,0.0001812661,0.0000752746,0.00003866864,0.0001127048,0.00004031888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003499709,0.00002659741,0.00005441048,0.0001515993,0.00001130142,0.00003670999,0.00001782876,0.000145312,0.9905623,0.0004879867,0.0003114326,0.008159607],"study_design_scores_gemma":[0.0000308301,0.0002207411,0.0005107502,0.00001841244,0.00001655824,0.0004631786,0.0000187769,0.004829308,0.9837307,0.0004389611,0.009702801,0.00001893069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1476382,0.03317404,0.8043593,0.001380131,0.001499798,0.0005568051,0.001453321,0.002918429,0.007019878],"genre_scores_gemma":[0.5107967,0.01880579,0.4539172,0.00138266,0.0003758664,0.001330139,0.001503298,0.0001238902,0.01176431],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001869812,"threshold_uncertainty_score":0.006007552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02182015181101446,"score_gpt":0.2682640652026113,"score_spread":0.2464439133915969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}