{"id":"W1994383643","doi":"10.1038/nbt.1892","title":"Jury remains out on simple models of transcription factor specificity","year":2011,"lang":"en","type":"letter","venue":"Nature Biotechnology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute; National Institutes of Health","keywords":"Jury; Simple (philosophy); Transcription factor; Computational biology; Factor (programming language); Biology; Computer science; Genetics; Gene; Political science; Law; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004947732,0.0007947724,0.00201705,0.0005274342,0.002248558,0.002622692,0.002611864,0.01040596,0.005130681],"category_scores_gemma":[0.01452333,0.0005560634,0.0008626049,0.0004070993,0.009006374,0.009255394,0.002570458,0.02247016,0.002566525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002490432,"about_ca_system_score_gemma":0.0008761704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006890742,"about_ca_topic_score_gemma":0.0008626337,"domain_scores_codex":[0.9987063,0.000288642,0.00008945585,0.0002145746,0.0005659896,0.0001350448],"domain_scores_gemma":[0.9907097,0.006980737,0.0002994369,0.0009863084,0.0005535813,0.0004704156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003133463,0.0001031132,0.0004456468,0.0003263499,0.0001012982,0.001320145,0.0002619028,0.002276514,0.002071701,0.5801607,0.3690865,0.04353265],"study_design_scores_gemma":[0.00009369276,0.00002832428,0.0001480397,0.00004160213,0.00002097006,0.0003126737,0.00007594703,0.003732217,0.001127347,0.9031743,0.09120189,0.0000430052],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.005477151,0.006209537,0.01806915,0.9378269,0.02133262,0.00001697034,0.0001289781,0.0003558816,0.01058288],"genre_scores_gemma":[0.2425585,0.01582294,0.01494798,0.6251329,0.06900766,0.0002987463,0.000256928,0.0003836494,0.03159073],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01040596,"threshold_uncertainty_score":0.02616644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01534078198552798,"score_gpt":0.2288067966941172,"score_spread":0.2134660147085892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}