{"id":"W1994395808","doi":"10.1007/s11627-012-9426-3","title":"Subcellular localization of sanguinarine biosynthetic enzymes in cultured opium poppy cells","year":2012,"lang":"en","type":"article","venue":"In Vitro Cellular & Developmental Biology - Plant","topic":"Berberine and alkaloids research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Sanguinarine; Subcellular localization; Benzylisoquinoline; Endoplasmic reticulum; Biology; Biochemistry; Green fluorescent protein; Cell biology; Opium Poppy; Vacuole; Cytosol; Compartmentalization (fire protection); Enzyme; Cytoplasm; Biosynthesis; Gene; Papaver","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001344632,0.0003150471,0.0002910203,0.0003133732,0.0003448073,0.0005363446,0.0002095364,0.0001812329,0.001099059],"category_scores_gemma":[0.00009002086,0.0001805718,0.0003198287,0.0003705093,0.000313865,0.0004363005,0.0003524295,0.0006150233,0.0004520316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004662886,"about_ca_system_score_gemma":0.0003153278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003938401,"about_ca_topic_score_gemma":0.004633638,"domain_scores_codex":[0.9998963,0.00001374955,0.00001117606,0.00002982576,0.00002012438,0.00002882762],"domain_scores_gemma":[0.9998822,0.00004401514,0.00001212271,0.00002343019,0.00001614696,0.00002207701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009040283,0.00000703575,0.0002206802,0.00002468117,0.000003961862,0.00007181887,0.00006091557,0.00002203816,0.9987292,0.0001379332,0.00001282701,0.0006186143],"study_design_scores_gemma":[0.000008177683,0.0000744775,0.01073153,0.000004794212,0.00002636311,0.0001778373,0.000141994,0.0005268589,0.9855693,0.00007556361,0.002656491,0.000006648605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838235,0.003002431,0.005376754,0.0001664823,0.00004662781,0.00002073387,0.0009772686,0.0001082978,0.006477763],"genre_scores_gemma":[0.9830468,0.001429167,0.004000476,0.00005281889,0.00001967449,0.00003385706,0.001872799,0.00004958101,0.009494862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003938401,"threshold_uncertainty_score":0.007830977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01899478519968891,"score_gpt":0.2659584184749302,"score_spread":0.2469636332752413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}