{"id":"W1994397972","doi":"10.2196/resprot.3353","title":"The Effects of Propofol Cardioplegia on Blood and Myocardial Biomarkers of Stress and Injury in Patients With Isolated Coronary Artery Bypass Grafting or Aortic Valve Replacement Using Cardiopulmonary Bypass: Protocol for a Single-Center Randomized Controlled Trial","year":2014,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cardiff University; National Institute for Health and Care Research; University Hospitals Bristol NHS Foundation Trust","keywords":"Medicine; Cardiopulmonary bypass; Propofol; Cardiology; Aortic valve replacement; Internal medicine; Cardiac surgery; Coronary artery bypass surgery; Placebo; Anesthesia; Cardioprotection; Artery; Myocardial infarction; Stenosis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004001029,0.0003396139,0.0020121,0.000320672,0.0002200776,0.00005828039,0.0001157662,0.00020922,0.000001619113],"category_scores_gemma":[0.00181121,0.0001740073,0.0004724288,0.0003050141,0.0006106124,0.00009029945,0.000178113,0.0004003708,1.123444e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00011312,"about_ca_system_score_gemma":0.0003225921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001481436,"about_ca_topic_score_gemma":0.000001529956,"domain_scores_codex":[0.9944747,0.002103308,0.001078637,0.0005688022,0.001189788,0.0005847359],"domain_scores_gemma":[0.995658,0.002554727,0.0004899797,0.0005409063,0.0005833213,0.0001731038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9146106,0.00205857,0.05093504,0.003387084,0.001727679,0.0000117251,0.0001742438,0.000001330834,0.02573911,0.000002729117,0.00003396351,0.001317883],"study_design_scores_gemma":[0.9446208,0.03122569,0.001931414,0.009951021,0.0002669958,0.00001460882,0.00005137465,0.0005022375,0.01113215,0.000006709909,0.0000962212,0.0002008072],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.4694983,0.000002597486,0.000008020123,0.00001626203,0.00001526826,0.5303848,0.00000862913,0.0000104011,0.00005570203],"genre_scores_gemma":[0.3956002,6.804899e-7,0.00005697205,0.000005617105,0.00007402157,0.6042095,0.000006445619,0.00003279767,0.00001372572],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.07389808,"threshold_uncertainty_score":0.7095811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02884077412447117,"score_gpt":0.383439879355932,"score_spread":0.3545991052314608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}