{"id":"W1994397972","doi":"10.2196/resprot.3353","title":"The Effects of Propofol Cardioplegia on Blood and Myocardial Biomarkers of Stress and Injury in Patients With Isolated Coronary Artery Bypass Grafting or Aortic Valve Replacement Using Cardiopulmonary Bypass: Protocol for a Single-Center Randomized Controlled Trial","year":2014,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cardiff University; National Institute for Health and Care Research; University Hospitals Bristol NHS Foundation Trust","keywords":"Medicine; Cardiopulmonary bypass; Propofol; Cardiology; Aortic valve replacement; Internal medicine; Cardiac surgery; Coronary artery bypass surgery; Placebo; Anesthesia; Cardioprotection; Artery; Myocardial infarction; Stenosis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02601071,0.00761821,0.01457123,0.00216056,0.003039584,0.004236587,0.00352963,0.008377838,0.04168957],"category_scores_gemma":[0.02702029,0.002801549,0.00508409,0.003044001,0.003871665,0.003756291,0.001824546,0.007372383,0.006996258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003916817,"about_ca_system_score_gemma":0.01116145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001693679,"about_ca_topic_score_gemma":0.003395755,"domain_scores_codex":[0.9791322,0.01287111,0.002240799,0.001904646,0.001717577,0.002133676],"domain_scores_gemma":[0.9880913,0.003109911,0.002473292,0.00157618,0.002852302,0.001896969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9714475,0.007398022,0.0003789573,0.005173733,0.001442637,0.0001160904,0.0001428087,0.0007768811,0.001192303,0.001064685,0.003925951,0.006940499],"study_design_scores_gemma":[0.9768499,0.01495973,0.0005830203,0.000539266,0.0005347073,0.00002275943,0.00003584272,0.0008629975,0.0002870242,0.0007021918,0.004577822,0.00004466074],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.005111732,0.0004022276,0.001325986,0.0003170174,0.0005466517,0.9905067,0.0008381996,0.000118939,0.000832619],"genre_scores_gemma":[0.005752738,0.0002203549,0.002025399,0.0002815124,0.0001034825,0.9909998,0.0001638151,0.000008618296,0.0004442947],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.04168957,"threshold_uncertainty_score":0.1394655,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02884077412447117,"score_gpt":0.383439879355932,"score_spread":0.3545991052314608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}