{"id":"W1994403941","doi":"10.3389/fonc.2014.00244","title":"Review of EGFRâ€‰TKIs in Metastatic NSCLC, Including Ongoing Trials","year":2014,"lang":"en","type":"review","venue":"Frontiers in Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Clinical trial; Epidermal growth factor receptor; Oncology; Lung cancer; Tyrosine kinase; Internal medicine; First line; Mutation; Cancer research; Cancer; Receptor; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007787967,0.0007619366,0.001390591,0.00283776,0.0002670593,0.0009818578,0.0008798468,0.0008501285,0.00557823],"category_scores_gemma":[0.001324904,0.0002938047,0.0008121936,0.003578025,0.0002579705,0.001207599,0.0004796037,0.001003518,0.001541371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006568629,"about_ca_system_score_gemma":0.001711042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001075528,"about_ca_topic_score_gemma":0.002290287,"domain_scores_codex":[0.9996755,0.00007128582,0.00008271563,0.00004506405,0.0001060043,0.00001940693],"domain_scores_gemma":[0.9994301,0.0002945786,0.0001046431,0.00001220737,0.0001291615,0.00002928223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001180042,0.00006621254,0.0001322763,0.09076469,0.0002377727,0.0001952227,0.00007185535,0.0003050864,0.001002895,0.001765124,0.0502729,0.855068],"study_design_scores_gemma":[0.00003503549,0.0001403755,0.001003855,0.02685907,0.0004950697,0.001212905,0.00005846518,0.00007092553,0.0002754428,0.0009800862,0.9688495,0.0000192057],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006382292,0.9989086,0.00004823491,0.0001772759,0.0001797044,0.000008667992,0.00003256437,0.000003602456,0.0005774786],"genre_scores_gemma":[0.0002952229,0.9990163,0.0000991253,0.0001751685,0.0001234645,0.000007329692,0.00002978928,7.526448e-7,0.0002528619],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00557823,"threshold_uncertainty_score":0.01866102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.143642522615381,"score_gpt":0.5224782663723971,"score_spread":0.3788357437570161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}