{"id":"W1994403941","doi":"10.3389/fonc.2014.00244","title":"Review of EGFRâ€‰TKIs in Metastatic NSCLC, Including Ongoing Trials","year":2014,"lang":"en","type":"review","venue":"Frontiers in Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Clinical trial; Epidermal growth factor receptor; Oncology; Lung cancer; Tyrosine kinase; Internal medicine; First line; Mutation; Cancer research; Cancer; Receptor; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003304563,0.0003539978,0.008283456,0.0008485902,0.00002465606,0.000004193831,0.0001824942,0.0002841411,0.0001116035],"category_scores_gemma":[0.002835288,0.0002603271,0.000647073,0.0007138178,0.00008682683,0.00004395819,0.00006951305,0.0004596097,0.00001431715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001892976,"about_ca_system_score_gemma":0.002043137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009305565,"about_ca_topic_score_gemma":0.000050282,"domain_scores_codex":[0.9952447,0.001479478,0.002347405,0.0004177906,0.000180716,0.000329914],"domain_scores_gemma":[0.9969913,0.001120464,0.001325474,0.0003980521,0.00006962715,0.00009511162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001980396,0.0001686462,0.00007672458,0.1278715,0.0005785178,0.0000736932,0.0001209342,4.165586e-7,6.567571e-8,0.00004366676,0.02701567,0.8440304],"study_design_scores_gemma":[0.001640641,0.0002679558,0.0000055509,0.2125066,0.00518485,0.00004410977,0.00005242214,0.000004443486,2.018071e-7,0.00007973515,0.7800773,0.0001362057],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000001077914,0.9887714,0.0005918613,0.0003472583,0.001546388,0.00298567,0.00003771249,0.00001450603,0.005704075],"genre_scores_gemma":[0.000002674523,0.9833609,0.01458446,0.0006600106,0.0001419892,0.0006609623,0.0002447152,0.00004779973,0.0002964763],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8438942,"threshold_uncertainty_score":0.9999849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.143642522615381,"score_gpt":0.5224782663723971,"score_spread":0.3788357437570161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}