{"id":"W1994408958","doi":"10.4161/auto.32154","title":"Autophagy is not required to sustain exercise and PRKAA1/AMPK activity but is important to prevent mitochondrial damage during physical activity","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":144,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Consiglio Nazionale delle Ricerche; Fondazione Telethon; Fondation Leducq","keywords":"Autophagy; AMPK; Biology; Skeletal muscle; Mitochondrion; Cell biology; Homeostasis; Endocrinology; Biochemistry; Protein kinase A; Apoptosis; Phosphorylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001379678,0.0002237737,0.0004461486,0.0002319689,0.0002638992,0.0003922077,0.000176688,0.0002907554,0.001893301],"category_scores_gemma":[0.0001474304,0.0001558399,0.0003534445,0.0001234221,0.0003445218,0.0003536073,0.0002638944,0.0006794633,0.0005074322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001946915,"about_ca_system_score_gemma":0.0002415605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003218149,"about_ca_topic_score_gemma":0.0008449221,"domain_scores_codex":[0.9997767,0.00002128257,0.00002775617,0.00008093179,0.00004063324,0.00005272066],"domain_scores_gemma":[0.9998324,0.00001069896,0.00007049554,0.00002726193,0.00001515692,0.00004398374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003447537,0.00002952342,0.0007060827,0.00006278131,0.00001036169,0.00004969452,0.0000103118,0.00002785503,0.9959197,0.0001083104,0.00006633001,0.002664265],"study_design_scores_gemma":[0.00006826025,0.0008483229,0.09341416,0.00003921479,0.00006513023,0.001370445,0.00008515216,0.00063662,0.8974757,0.0002944081,0.005687132,0.00001546219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991313,0.002878845,0.002973624,0.0002756553,0.00007005194,0.00001865729,0.0005450544,0.0001015543,0.001823593],"genre_scores_gemma":[0.9935967,0.0009331452,0.001308579,0.00009241547,0.00001870755,0.0000431913,0.0005825623,0.00003862143,0.00338613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001893301,"threshold_uncertainty_score":0.006333768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0120421847712835,"score_gpt":0.293555761741312,"score_spread":0.2815135769700285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}