{"id":"W1994408958","doi":"10.4161/auto.32154","title":"Autophagy is not required to sustain exercise and PRKAA1/AMPK activity but is important to prevent mitochondrial damage during physical activity","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":144,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Consiglio Nazionale delle Ricerche; Fondazione Telethon; Fondation Leducq","keywords":"Autophagy; AMPK; Biology; Skeletal muscle; Mitochondrion; Cell biology; Homeostasis; Endocrinology; Biochemistry; Protein kinase A; Apoptosis; Phosphorylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002835566,0.0006202253,0.001088084,0.000268199,0.0002969326,0.0001008757,0.0003075252,0.0002500926,0.0002974829],"category_scores_gemma":[0.0002151651,0.0005789702,0.0003354441,0.0004442081,0.0001219443,0.000361068,0.0003540929,0.0004121243,0.0001689679],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002497955,"about_ca_system_score_gemma":0.0002492957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000262397,"about_ca_topic_score_gemma":0.000008759533,"domain_scores_codex":[0.9964098,0.0001583216,0.0004298555,0.001256491,0.0007745054,0.0009710595],"domain_scores_gemma":[0.997074,0.0001419951,0.0002172382,0.001291606,0.000140374,0.001134776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004523395,0.002207357,0.0003061985,0.000352304,0.0002536188,0.000353219,0.00406393,0.00000962276,0.9378945,0.0002634095,0.002120372,0.04765213],"study_design_scores_gemma":[0.003093519,0.0007793346,0.1287426,0.0001950461,0.0002364767,0.00002811552,0.00006246086,0.001578882,0.8619571,0.000357202,0.002414127,0.000555169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936576,0.0001059164,0.0003830249,0.002702069,0.0004325713,0.002038521,0.0001039378,0.0002914635,0.000284877],"genre_scores_gemma":[0.9899076,0.00005522797,0.0005051293,0.002202937,0.001006477,0.0002552631,0.000009706022,0.00011031,0.005947385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1284364,"threshold_uncertainty_score":0.9996662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0120421847712835,"score_gpt":0.293555761741312,"score_spread":0.2815135769700285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}