{"id":"W1994419078","doi":"10.1074/jbc.m113.453712","title":"Vac14 Protein Multimerization Is a Prerequisite Step for Fab1 Protein Complex Assembly and Function","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital; Centre for Addiction and Mental Health; Toronto Metropolitan University","funders":"","keywords":"Signal transducing adaptor protein; Cell biology; Phosphatidylinositol; Organelle; Biology; Phosphatase; Ubiquitin; Biochemistry; Phosphorylation; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001228736,0.0003293718,0.0002890459,0.0001985296,0.0002124658,0.0003652166,0.0002352073,0.0003208979,0.001172648],"category_scores_gemma":[0.0001738109,0.0002019299,0.0003136894,0.0001231807,0.0001289015,0.0002109052,0.0003664975,0.0003317502,0.000704362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000523717,"about_ca_system_score_gemma":0.0001725257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000931107,"about_ca_topic_score_gemma":0.0008984425,"domain_scores_codex":[0.999796,0.00002495776,0.00001966583,0.00004734317,0.0000569667,0.00005516323],"domain_scores_gemma":[0.9998637,0.0000142216,0.00004772937,0.00001685256,0.00002648561,0.00003105777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003397683,0.000004829581,0.000696698,0.0000211137,0.000005795381,0.00005825189,0.000008940231,0.00003640304,0.998193,0.0001105635,0.00004142347,0.0007890235],"study_design_scores_gemma":[0.000007118232,0.00008186947,0.03148381,0.000006204406,0.00001294304,0.00093732,0.00003288011,0.001348831,0.9616345,0.00009461569,0.00435403,0.000005924494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943336,0.001056506,0.003434909,0.00005180714,0.00001183882,0.00001365226,0.0003759723,0.0001046049,0.0006171266],"genre_scores_gemma":[0.9944491,0.0003283884,0.002470881,0.0000186441,0.000004613918,0.00001896723,0.001248942,0.00003004653,0.001430394],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001172648,"threshold_uncertainty_score":0.003922939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02094684140538844,"score_gpt":0.2352784927642453,"score_spread":0.2143316513588569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}