{"id":"W1994498173","doi":"10.1002/hep.23233","title":"Hepatic Drug Transporters, Old and New","year":2009,"lang":"en","type":"letter","venue":"Hepatology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"ATP-binding cassette transporter; Transporter; Solute carrier family; Abcg2; Organic anion-transporting polypeptide; Organic cation transport proteins; Drug; Pharmacology; Pharmacogenomics; Biology; Multiple drug resistance; Drug metabolism; Multidrug Resistance-Associated Proteins; Drug resistance; Multidrug resistance-associated protein 2; Major facilitator superfamily; Membrane transport protein; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000811628,0.0004356121,0.001134965,0.0002196849,0.00005550352,0.00001125383,0.0001333075,0.001013343,0.0004111052],"category_scores_gemma":[0.000005132094,0.000367358,0.000221411,0.0001147679,0.0001218726,0.00003378304,0.000006613643,0.001441448,0.0000616164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004435003,"about_ca_system_score_gemma":0.0002520403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002711331,"about_ca_topic_score_gemma":0.0001899024,"domain_scores_codex":[0.9980507,0.00004020605,0.0004474766,0.0006100851,0.0002796824,0.0005718157],"domain_scores_gemma":[0.9991305,0.00004200049,0.0001240207,0.0004617155,0.00003565284,0.0002061168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009103982,0.00003394465,0.01148945,0.000698961,0.000121357,0.01043232,0.0002597708,2.480305e-8,0.00007409531,0.0001469412,0.974013,0.002639082],"study_design_scores_gemma":[0.0013434,0.0001518481,0.002076895,0.0002635015,0.0007080818,0.0007327673,0.00001127964,0.00001955256,0.0002519907,0.001286297,0.9927742,0.0003801501],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0278665,0.003359531,0.0004264516,0.9633178,0.0008397681,0.0006221496,0.00003045652,0.0002201962,0.003317202],"genre_scores_gemma":[0.02211219,0.001365213,0.001581966,0.9107547,0.002106935,0.00001590426,0.0008774636,0.00009717546,0.06108846],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.05777126,"threshold_uncertainty_score":0.9998778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01621522389552315,"score_gpt":0.2349189989508382,"score_spread":0.218703775055315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}