{"id":"W1994539334","doi":"10.1258/ebm.2011.010324","title":"Medusa structure of the gene regulatory network: dominance of transcription factors in cancer subtype classification","year":2011,"lang":"en","type":"article","venue":"Experimental Biology and Medicine","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Air Force Office of Scientific Research","keywords":"Biology; Gene; Gene expression; microRNA; Genetics; Gene regulatory network; Regulation of gene expression; Effector; Transcription factor; Computational biology; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007410147,0.00007639123,0.000136017,0.00001536984,0.00002497437,3.113535e-7,0.00008094685,0.0001399292,0.00003406929],"category_scores_gemma":[0.000004727538,0.0000470639,0.00002223057,0.00004807657,0.0003349257,0.00000224056,0.00002488691,0.00005455192,3.609621e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006742801,"about_ca_system_score_gemma":0.00001801694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001064193,"about_ca_topic_score_gemma":0.00007177203,"domain_scores_codex":[0.9995292,0.00003088437,0.0002081579,0.000105994,0.00003014873,0.00009555317],"domain_scores_gemma":[0.9996963,0.000003926859,0.0001292291,0.000133533,0.00001631081,0.00002076603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009487199,0.00001410706,0.02214059,0.000007427631,0.00001260176,3.52709e-8,0.001029623,0.000003925433,0.9749563,0.0008074229,0.000100806,0.0008322834],"study_design_scores_gemma":[0.0004419803,0.0001916307,0.1518525,0.0000289814,0.000008425804,0.000001652633,0.0003901439,0.00002376843,0.8465393,0.0002546868,0.0002195981,0.00004729173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914274,0.007845485,0.00008664366,0.00003424724,0.0003053298,0.0001153946,0.00001188121,0.000001052301,0.00017259],"genre_scores_gemma":[0.9991687,0.0004515746,0.0001487834,0.00007477131,0.00008328005,0.00000388389,0.0000393498,0.000003717203,0.00002594322],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1297119,"threshold_uncertainty_score":0.191921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02255947430656028,"score_gpt":0.2758206455359793,"score_spread":0.253261171229419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}