{"id":"W1994539986","doi":"10.1038/sj.jcbfm.9600197","title":"Positron Emission Tomography Quantification of [<sup>11</sup>C]-Harmine Binding to Monoamine Oxidase-A in the Human Brain","year":2005,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Harmine; Positron emission tomography; Brain positron emission tomography; Monoamine oxidase; Human brain; Monoamine oxidase A; Monoamine oxidase B; Nuclear medicine; Radiochemistry; Chemistry; Nuclear magnetic resonance; Physics; Neuroscience; Medicine; Preclinical imaging; Biology; Enzyme; In vivo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003189517,0.0003907748,0.0003319299,0.0001600512,0.0001054421,0.0004420038,0.0004009341,0.0004504352,0.0003865768],"category_scores_gemma":[0.0007661336,0.000275849,0.0002898528,0.0001362116,0.0002180362,0.0002422104,0.0001612477,0.0002432507,0.0001472059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003525021,"about_ca_system_score_gemma":0.0003975783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004120915,"about_ca_topic_score_gemma":0.00410305,"domain_scores_codex":[0.9999113,0.00003607013,0.00000441298,0.00002599385,0.00001472745,0.000007464541],"domain_scores_gemma":[0.9999064,0.0000424634,0.00002109738,0.00001309155,0.00001191478,0.00000501473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00157076,0.0001063334,0.01646829,0.0002753035,0.0004750829,0.000537328,0.0001561943,0.1430427,0.7982557,0.001142683,0.0003313755,0.03763813],"study_design_scores_gemma":[0.0002327004,0.002677687,0.1206634,0.00003741763,0.0004632235,0.003637192,0.000185819,0.5252984,0.34017,0.002208369,0.004311523,0.0001143035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8664251,0.003028497,0.1284858,0.0001176888,0.00001024378,0.00007561534,0.0003446195,0.0002935959,0.001218918],"genre_scores_gemma":[0.9672855,0.001441814,0.02970791,0.00004517959,0.000006276691,0.0001159488,0.0003578363,0.00003780776,0.001001756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004120915,"threshold_uncertainty_score":0.008193851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02781804670621781,"score_gpt":0.2948710902568809,"score_spread":0.2670530435506631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}