{"id":"W199454418","doi":"10.1038/npre.2010.4232.1","title":"Phosphatidylserine polarization is required for proper Cdc42 localization and for development of cell polarity.","year":2010,"lang":"en","type":"preprint","venue":"Nature Precedings","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Canadian Institutes of Health Research; McMaster University","keywords":"Cell polarity; Phosphatidylserine; Biophysics; CDC42; Cell biology; Vesicle; Saccharomyces cerevisiae; Cell cortex; Fluorescence anisotropy; Exocytosis; Fluorescence recovery after photobleaching; Photobleaching; Cytosol; Chemistry; Biology; Fluorescence; Membrane; Cell; Yeast; Biochemistry; Optics; Actin; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003572438,0.0002704369,0.0005096522,0.0001675187,0.0001053849,0.00003535777,0.0000930831,0.001289273,0.0000431097],"category_scores_gemma":[0.0007201937,0.0002339571,0.0001025184,0.0001161719,0.00005188745,0.00008393665,0.0001301258,0.00059467,9.224542e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006389257,"about_ca_system_score_gemma":0.0002921253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001048279,"about_ca_topic_score_gemma":0.00000323848,"domain_scores_codex":[0.9985765,0.000009386215,0.0004677997,0.0004799172,0.0002517678,0.0002146219],"domain_scores_gemma":[0.9983915,0.0000895828,0.0003577493,0.0002351405,0.0008042871,0.00012176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001262883,0.0002935498,0.008641622,0.009493507,0.0002404909,2.379624e-7,0.002662629,0.000004093729,0.9590892,0.0009338017,0.002835592,0.0145424],"study_design_scores_gemma":[0.002534842,0.0001948234,0.002877839,0.0006745062,0.0003576685,0.000002175402,0.00004284367,0.005311836,0.9509966,0.000885865,0.03583559,0.000285372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8259765,0.002927677,0.1583927,0.001559852,0.001970176,0.006956902,0.0002890829,0.0001817111,0.001745439],"genre_scores_gemma":[0.807907,0.00006186511,0.1867632,0.0009566323,0.0002767914,0.0003089558,0.001371761,0.00006587298,0.002287876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.033,"threshold_uncertainty_score":0.9944051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0188241535280178,"score_gpt":0.2889762862855615,"score_spread":0.2701521327575437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}