{"id":"W1994558354","doi":"10.1038/gt.2015.22","title":"Cochlear protection against cisplatin by viral transfection of X-linked inhibitor of apoptosis protein across round window membrane","year":2015,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Hearing, Cochlea, Tinnitus, Genetics","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"XIAP; Round window; Cochlea; Inhibitor of apoptosis; Inner ear; Cisplatin; Apoptosis; Transfection; Ototoxicity; Biology; Hearing loss; Cell biology; Transgene; Cancer research; Programmed cell death; Medicine; Anatomy; Gene; Caspase; Chemotherapy; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002238136,0.0004132003,0.000342821,0.0002757151,0.0002379212,0.0003315368,0.0003412679,0.000461614,0.001766851],"category_scores_gemma":[0.0001930614,0.0001989134,0.0003623957,0.0001815458,0.0003834833,0.0005475422,0.0002446554,0.000944131,0.0003382388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003145132,"about_ca_system_score_gemma":0.0005096137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007654498,"about_ca_topic_score_gemma":0.0006217589,"domain_scores_codex":[0.9998272,0.00002654407,0.00001479287,0.00003833392,0.00003718145,0.00005593303],"domain_scores_gemma":[0.9998764,0.00003486004,0.00002886044,0.00002104647,0.00001526645,0.0000235914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003461563,0.000060861,0.0000609351,0.0000324337,0.000008041796,0.00005030837,0.00002753629,0.00006489162,0.997883,0.0003653677,0.00005017713,0.001050135],"study_design_scores_gemma":[0.00005550037,0.0006646261,0.0007415129,0.000005201433,0.00002468406,0.0001345041,0.00003249634,0.0007708084,0.9965082,0.00007713168,0.000980302,0.000005026352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910237,0.001762911,0.004675795,0.0001941907,0.0001164066,0.00007260772,0.0001417144,0.0001309253,0.00188181],"genre_scores_gemma":[0.9946694,0.001009244,0.001583165,0.00004251529,0.000013275,0.00004598187,0.0001637469,0.00001572381,0.002457006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001766851,"threshold_uncertainty_score":0.005910754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06253737917088607,"score_gpt":0.290239711026957,"score_spread":0.2277023318560709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}