{"id":"W1994558354","doi":"10.1038/gt.2015.22","title":"Cochlear protection against cisplatin by viral transfection of X-linked inhibitor of apoptosis protein across round window membrane","year":2015,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Hearing, Cochlea, Tinnitus, Genetics","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"XIAP; Round window; Cochlea; Inhibitor of apoptosis; Inner ear; Cisplatin; Apoptosis; Transfection; Ototoxicity; Biology; Hearing loss; Cell biology; Transgene; Cancer research; Programmed cell death; Medicine; Anatomy; Gene; Caspase; Chemotherapy; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007122668,0.0002710117,0.0003941586,0.0001097233,0.0001387222,0.00004691481,0.0002792271,0.0002230969,0.00001715491],"category_scores_gemma":[0.0001974744,0.0002691553,0.0001253047,0.0005555779,0.0002374958,0.000200359,0.00003813092,0.0002832471,0.00001818406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001003873,"about_ca_system_score_gemma":0.0001356833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002129394,"about_ca_topic_score_gemma":0.00001906077,"domain_scores_codex":[0.9973821,0.0003716784,0.0006187221,0.0005071031,0.0006812185,0.0004391895],"domain_scores_gemma":[0.9988528,0.00004088394,0.0003022963,0.000460406,0.00019412,0.0001494994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008000565,0.00026639,0.00006587681,0.00005143265,0.00001509,7.433521e-7,0.00205611,0.0005248323,0.9782288,0.00001038972,0.00004081783,0.01793948],"study_design_scores_gemma":[0.0027502,0.001337831,0.000203783,0.00004542461,0.00000622984,0.000004967972,0.0001192005,0.000548116,0.9932926,0.00009263746,0.001354042,0.0002450112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946365,0.0001214728,0.002595671,0.0001451568,0.0002931265,0.001871292,0.0000604094,0.0001067924,0.0001695954],"genre_scores_gemma":[0.9985597,0.0001503153,0.0005381485,0.0001208418,0.0001626103,0.0001192679,0.000008778567,0.00006516588,0.0002752316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01769447,"threshold_uncertainty_score":0.999976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06253737917088607,"score_gpt":0.290239711026957,"score_spread":0.2277023318560709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}