{"id":"W1994608908","doi":"10.1002/ddr.20290","title":"Small molecule inhibitors of Aβ‐aggregation and neurotoxicity","year":2009,"lang":"en","type":"article","venue":"Drug Development Research","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"","keywords":"Basal forebrain; Neuroscience; Neurotoxicity; Cholinergic neuron; Cholinergic; Amyloid (mycology); Drug; Extracellular; Forebrain; Alzheimer's disease; Pharmacology; Chemistry; Disease; Medicine; Psychology; Pathology; Toxicity; Biochemistry; Internal medicine; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001693202,0.0005750621,0.0005319215,0.0006178468,0.0002123617,0.0003855799,0.0002911582,0.0003557281,0.004371691],"category_scores_gemma":[0.0001258889,0.0001058523,0.0003100865,0.0004229915,0.0001438061,0.0003140452,0.0002373126,0.0006350239,0.001453372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002496756,"about_ca_system_score_gemma":0.0001954206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004155027,"about_ca_topic_score_gemma":0.0008589673,"domain_scores_codex":[0.9999386,0.00001118684,0.000006506056,0.000009155561,0.00002019841,0.00001432995],"domain_scores_gemma":[0.9999601,0.00000960744,0.000007334119,0.000002117082,0.00001045601,0.00001035465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001425386,0.00114138,0.0006307618,0.004961934,0.0002187462,0.001396214,0.0001052062,0.001620016,0.4048364,0.007422396,0.01857838,0.5576633],"study_design_scores_gemma":[0.001674986,0.008397453,0.006520406,0.0007427278,0.0004541668,0.004213028,0.00007549829,0.002219041,0.310357,0.002483163,0.662784,0.00007843486],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1048317,0.8496594,0.005681801,0.001015249,0.001072993,0.0002711444,0.001035367,0.0003548874,0.03607744],"genre_scores_gemma":[0.326997,0.6342216,0.005075347,0.001192674,0.0004783316,0.0002804943,0.001390259,0.00002745463,0.03033681],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004371691,"threshold_uncertainty_score":0.01462477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06815916220801313,"score_gpt":0.3541991901073875,"score_spread":0.2860400278993743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}