{"id":"W1994619498","doi":"10.1074/jbc.m113.534172","title":"De Novo Synthesis of Steroids and Oxysterols in Adipocytes","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Oxysterol; Adipocyte; Paracrine signalling; Biology; CYP27A1; Endocrinology; Internal medicine; Cholesterol; Adipose tissue; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000240155,0.00008345518,0.0004011388,0.00002933308,0.000006822709,0.000009393954,0.00007319992,0.0001411451,0.0002165572],"category_scores_gemma":[0.0004057164,0.00004984056,0.00007836307,0.00005071037,0.00008912751,0.00004239802,0.00002825978,0.0002136369,0.000001668617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002057419,"about_ca_system_score_gemma":0.00002749715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000504163,"about_ca_topic_score_gemma":1.33167e-7,"domain_scores_codex":[0.9992777,0.00002583603,0.000390118,0.00008010487,0.00009309041,0.0001331711],"domain_scores_gemma":[0.999391,0.000142088,0.0001773558,0.00008106235,0.00007264436,0.0001359059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001065967,0.0001070087,0.136942,0.00009777989,0.00002617331,0.000023067,0.00004065104,4.211997e-7,0.8533597,0.000001189235,0.00004722018,0.009248149],"study_design_scores_gemma":[0.0009927861,0.0001422473,0.4950246,0.0002599609,0.00003858634,0.0008460943,0.000143119,0.00001015702,0.5017337,0.00009428421,0.0006561434,0.00005840902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976345,0.001175086,0.000007443756,0.0004237931,0.00002302801,0.00004727354,0.000001915664,0.000003143199,0.0006838419],"genre_scores_gemma":[0.9987928,0.000233844,0.0005110845,0.0001774005,0.0001947742,0.000003201019,4.048413e-7,0.000003828965,0.00008269849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3580826,"threshold_uncertainty_score":0.2371149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01810310723258341,"score_gpt":0.2490616783421471,"score_spread":0.2309585711095637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}