{"id":"W1994645646","doi":"10.1002/mc.20218","title":"Dysregulation of the endothelial cellular response to oxidative stress in cancer","year":2006,"lang":"en","type":"review","venue":"Molecular Carcinogenesis","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Cell biology; Biology; p38 mitogen-activated protein kinases; MAPK/ERK pathway; Signal transduction; Oxidative stress; Endothelial stem cell; Vascular permeability; Actin cytoskeleton; Endothelium; Extravasation; Actin; Kinase; Cytoskeleton; Cell; Immunology; Biochemistry; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003151854,0.0004662202,0.0008650602,0.0002032519,0.00005662563,0.00001611318,0.0006058466,0.0004391669,0.00001697287],"category_scores_gemma":[0.00006842429,0.0003588873,0.0008391772,0.0005831671,0.00008923411,0.000002409454,0.0003005358,0.0001077449,0.000003781574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001499261,"about_ca_system_score_gemma":0.0005560244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004983295,"about_ca_topic_score_gemma":0.0003293445,"domain_scores_codex":[0.9972892,0.0006897426,0.0006349888,0.000684591,0.0003420255,0.0003594289],"domain_scores_gemma":[0.9984814,0.00003230836,0.0003600543,0.0009211876,0.0001305165,0.00007453848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002895259,0.0001609181,0.001810224,0.002458391,0.0003483401,0.00002770822,0.00006093428,0.001440645,0.821687,0.00003633076,0.000668413,0.1710115],"study_design_scores_gemma":[0.0002367985,0.00008331372,0.0006303837,0.001455441,0.0003706774,0.000004175333,0.00001042008,0.000002801343,0.4884769,0.000003759666,0.5083031,0.0004221886],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08771177,0.909678,0.0005446697,0.00003418,0.0002346427,0.000953552,0.000767702,0.000005321805,0.00007014965],"genre_scores_gemma":[0.08093737,0.9164853,0.0002025013,0.0001271892,0.000358201,0.0007052163,0.0003015107,0.0001561532,0.0007265691],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5076347,"threshold_uncertainty_score":0.9998863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02349396311045603,"score_gpt":0.3019140641787961,"score_spread":0.27842010106834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}