{"id":"W1994677849","doi":"10.1016/j.vaccine.2008.09.041","title":"Naturally-occurring human serum antibodies to inner core lipopolysaccharide epitopes of Neisseria meningitidis protect against invasive meningococcal disease caused by isolates displaying homologous inner core structures","year":2008,"lang":"en","type":"article","venue":"Vaccine","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Biological Sciences","funders":"Wellcome Trust","keywords":"Neisseria meningitidis; Heptose; Epitope; Lipopolysaccharide; Antibody; Biology; Inner core; Neisseriaceae; Microbiology; Epitope mapping; Mutant; Molecular biology; Immunology; Bacteria; Biochemistry; Antibiotics; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003375191,0.0004173048,0.0002163777,0.0001829136,0.0001560395,0.0002264355,0.0002443155,0.0003407446,0.001183502],"category_scores_gemma":[0.0005309613,0.0001311113,0.0002065412,0.00007813353,0.0002522432,0.0001610883,0.0001996448,0.0006021733,0.0003166726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002388915,"about_ca_system_score_gemma":0.0001949267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000727413,"about_ca_topic_score_gemma":0.0007205917,"domain_scores_codex":[0.9998616,0.00003712738,0.000006978091,0.00001862202,0.00002743914,0.00004817248],"domain_scores_gemma":[0.9997764,0.00007715893,0.00003094251,0.00003355851,0.00003261119,0.00004920749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00103237,0.0007656328,0.004454369,0.00006086235,0.00003756797,0.000184526,0.00009334074,0.0001885898,0.9856361,0.0002299562,0.0003623712,0.00695427],"study_design_scores_gemma":[0.0004543722,0.01184944,0.05980341,0.00004068414,0.0001121115,0.002306029,0.0001954359,0.002699444,0.917721,0.0003814427,0.004420897,0.00001576995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983109,0.0002753631,0.0005622791,0.00004903556,0.00002379766,0.0000167835,0.00003707206,0.00001742524,0.0007073344],"genre_scores_gemma":[0.9989541,0.000115537,0.0002462598,0.00005642297,0.00001643873,0.000006830251,0.000131083,0.000004284072,0.0004690628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001183502,"threshold_uncertainty_score":0.003959239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02053944657868249,"score_gpt":0.2643820355534254,"score_spread":0.243842588974743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}