{"id":"W1994684879","doi":"10.1002/cmdc.201000326","title":"Thalidomide Derivatives for the Treatment of Neuroinflammation","year":2010,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Thalidomide; Experimental autoimmune encephalomyelitis; Medicine; Multiple sclerosis; Pharmacology; Drug; Immunology; Multiple myeloma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001348015,0.0001792416,0.0001669733,0.0001514743,0.0000788566,0.0001290247,0.0001357089,0.0001589017,0.0005780308],"category_scores_gemma":[0.00007474701,0.00006813632,0.0000943904,0.0001284095,0.0001301698,0.0001200062,0.0000888123,0.0003498664,0.0001143784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003111808,"about_ca_system_score_gemma":0.0001854272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005910379,"about_ca_topic_score_gemma":0.001414387,"domain_scores_codex":[0.9999621,0.00001048969,0.000003190538,0.00000487664,0.00001158039,0.000007704453],"domain_scores_gemma":[0.99998,0.000003893747,0.000006461679,0.000001906027,0.000003205922,0.000004566753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007561167,0.0001764248,0.0003570864,0.0003941956,0.00003469981,0.0003522934,0.00006562335,0.0007622723,0.9275851,0.001189544,0.000473691,0.06785299],"study_design_scores_gemma":[0.0006775187,0.00672564,0.004064543,0.00005859375,0.0001039703,0.001740374,0.00002486409,0.001254313,0.9399419,0.000338652,0.04504578,0.0000238098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8275089,0.1564863,0.007132217,0.0006226855,0.0001244657,0.0002504378,0.0002453462,0.0001033923,0.007526265],"genre_scores_gemma":[0.9530808,0.03945892,0.004367784,0.0001324044,0.00003121163,0.00004649593,0.0001891889,0.000006678001,0.002686409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005910379,"threshold_uncertainty_score":0.002257764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05025797420761865,"score_gpt":0.3430382566716857,"score_spread":0.2927802824640671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}