{"id":"W1994702653","doi":"10.1016/j.ymthe.2004.08.016","title":"Retroviral transduction of hematopoietic cells differentiated from human embryonic stem cell-derived CD45negPFV hemogenic precursors","year":2004,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"","keywords":"Biology; Haematopoiesis; Embryonic stem cell; Transduction (biophysics); Transgene; Cell biology; Progenitor cell; Hemangioblast; Stem cell; CD34; Molecular biology; Retrovirus; Cell culture; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002520961,0.0003162635,0.0002228887,0.0001809185,0.0001413798,0.0003132119,0.0001937908,0.0001981852,0.0009603218],"category_scores_gemma":[0.0001364839,0.0001266033,0.0001311741,0.0001494064,0.0002007027,0.0001303233,0.0001959508,0.0004416287,0.0003016913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002189088,"about_ca_system_score_gemma":0.0001804769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002566976,"about_ca_topic_score_gemma":0.0003965361,"domain_scores_codex":[0.9998214,0.00003066517,0.00002031884,0.00003434952,0.00006878738,0.00002457407],"domain_scores_gemma":[0.9999262,0.00002068575,0.00001706706,0.00001424312,0.000008774849,0.0000129438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001975244,0.00001222195,0.0001383786,0.00001422035,0.00000266326,0.0000238356,0.00001662876,0.00005719385,0.9980267,0.0002797783,0.00002738118,0.001381322],"study_design_scores_gemma":[0.000006290945,0.00008045057,0.0008823518,0.000002124301,0.000008107447,0.0001513509,0.00001052933,0.0006566622,0.9957968,0.00003873583,0.002364971,0.000001694912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9741701,0.0005099527,0.02170878,0.00004691938,0.0000443034,0.0002075733,0.0005574464,0.0001637377,0.002591213],"genre_scores_gemma":[0.9689178,0.0008135976,0.0214619,0.00005325285,0.0000152277,0.0002056636,0.001882211,0.00005151421,0.006598745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009603218,"threshold_uncertainty_score":0.003212571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006754603645677253,"score_gpt":0.2447535704958178,"score_spread":0.2379989668501406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}