{"id":"W1994736776","doi":"10.1182/blood-2007-07-099309","title":"Guanine exchange factor RalGDS mediates exocytosis of Weibel-Palade bodies from endothelial cells","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Exocytosis; Exocyst; Cell biology; Guanine nucleotide exchange factor; Calmodulin; Chemistry; Signal transduction; Biology; Biochemistry; Secretion","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001079096,0.00017563,0.0002334628,0.0001776526,0.000171194,0.0003317309,0.0001370871,0.0002405791,0.0007815564],"category_scores_gemma":[0.0001248402,0.00008952674,0.0001911519,0.00008581993,0.0001679709,0.0002257727,0.0003277102,0.0003483727,0.0004180203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003738108,"about_ca_system_score_gemma":0.0001054556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004761967,"about_ca_topic_score_gemma":0.0006548763,"domain_scores_codex":[0.9999247,0.00001484408,0.000005512865,0.00001494921,0.00001619224,0.00002380619],"domain_scores_gemma":[0.9999465,0.00001043679,0.000009443472,0.000007359818,0.000006154333,0.00002012079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007756659,0.000005357303,0.0002086213,0.00001913643,0.000003547935,0.0001227634,0.00001066752,0.00004364099,0.9983047,0.0001922745,0.00006644766,0.0009451641],"study_design_scores_gemma":[0.0000316611,0.00007783488,0.01454923,0.000007253414,0.00001159959,0.0005304497,0.00004427076,0.003279502,0.9752856,0.0001705323,0.006004189,0.000007922086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939739,0.001760159,0.002227625,0.0001927618,0.00001934165,0.000009932605,0.0001811343,0.00007220596,0.001562856],"genre_scores_gemma":[0.9960343,0.0005089227,0.0009892934,0.00004419065,0.000009553802,0.00000973134,0.0002567228,0.00001324993,0.002134002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007815564,"threshold_uncertainty_score":0.00271219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0138348350239956,"score_gpt":0.2014085997867253,"score_spread":0.1875737647627297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}