{"id":"W1994736776","doi":"10.1182/blood-2007-07-099309","title":"Guanine exchange factor RalGDS mediates exocytosis of Weibel-Palade bodies from endothelial cells","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Exocytosis; Exocyst; Cell biology; Guanine nucleotide exchange factor; Calmodulin; Chemistry; Signal transduction; Biology; Biochemistry; Secretion","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003259074,0.000147406,0.0001895516,0.00003217293,0.00005091082,0.000003991639,0.0001323353,0.0001507862,0.0002297282],"category_scores_gemma":[0.00001042932,0.0001374203,0.0001270907,0.00003225263,0.00008746147,0.000003124929,0.00003287199,0.0000561562,0.00001248911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002731018,"about_ca_system_score_gemma":0.00002994768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001088962,"about_ca_topic_score_gemma":0.00009019169,"domain_scores_codex":[0.9992166,0.00002381892,0.0002032862,0.0002403953,0.000140441,0.0001755097],"domain_scores_gemma":[0.9995774,0.000009814203,0.00007856209,0.0002291764,0.00004232578,0.00006269454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005725987,0.0001556734,0.01311459,0.00001810169,0.00008920096,0.00001200518,0.0004915894,0.000001230092,0.9859009,0.000001869883,0.00007647743,0.00008112919],"study_design_scores_gemma":[0.001349487,0.0001976107,0.008447627,0.000008960632,0.00006198501,0.000004561207,0.00003342983,0.000003509869,0.976123,0.00001287092,0.0136047,0.0001522939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957247,0.002748744,0.0003992784,0.00002744497,0.0001458682,0.0001018892,0.0004706134,0.00001529786,0.0003661629],"genre_scores_gemma":[0.9939818,0.002665238,0.0004425093,0.00003774736,0.0004124802,0.00001007228,0.00195004,0.00002148055,0.0004785791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01352823,"threshold_uncertainty_score":0.5603838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0138348350239956,"score_gpt":0.2014085997867253,"score_spread":0.1875737647627297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}