{"id":"W1994765179","doi":"10.1124/jpet.104.072769","title":"Attentuation of Cardiac Stunning by Losartan in a Cellular Model of Ischemia and Reperfusion Is Accompanied by Increased Sarcoplasmic Reticulum Ca2+ Stores and Prevention of Cytosolic Ca2+ Elevation","year":2004,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Losartan; Ischemia; Internal medicine; Chemistry; Endoplasmic reticulum; Angiotensin II; Endocrinology; Myocyte; Medicine; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004049682,0.001033797,0.001582037,0.0004092861,0.0004617861,0.0006498205,0.0006545528,0.0007374602,0.002464732],"category_scores_gemma":[0.0003263801,0.0003824871,0.0006306244,0.0003312035,0.0008264226,0.0008991855,0.0003371622,0.002419326,0.0004101465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004642303,"about_ca_system_score_gemma":0.000707766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001358071,"about_ca_topic_score_gemma":0.00290666,"domain_scores_codex":[0.9997116,0.00003784286,0.00003127249,0.00003739719,0.00003986427,0.0001419889],"domain_scores_gemma":[0.9996397,0.00004098969,0.00007840023,0.00006389888,0.00003110413,0.0001458427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005430074,0.0004726586,0.0002040048,0.0001422567,0.00003652783,0.0002996103,0.00006613893,0.0001223622,0.9900343,0.0002703429,0.0002110581,0.002710644],"study_design_scores_gemma":[0.0003913377,0.00401084,0.006504803,0.00001728403,0.0001053444,0.0002532444,0.0001233619,0.001582272,0.9858034,0.000133821,0.001051845,0.00002255757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913843,0.002877042,0.002742158,0.0004613577,0.0002351982,0.00006635177,0.0003706249,0.000351109,0.001511883],"genre_scores_gemma":[0.993067,0.00117394,0.001939581,0.0001153602,0.0001058046,0.0001166931,0.0006488222,0.0000372604,0.00279544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002464732,"threshold_uncertainty_score":0.008245409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01451234947911334,"score_gpt":0.3037966129087958,"score_spread":0.2892842634296824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}