{"id":"W1994788263","doi":"10.2741/begleit","title":"Clinical applications of quinone-containing alkylating agents","year":2000,"lang":"en","type":"review","venue":"Frontiers in bioscience","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"","keywords":"Quinone; Chemistry; Moiety; Combinatorial chemistry; Biochemistry; Stereochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005128618,0.0001982654,0.0006661649,0.0001319982,0.00005243169,0.00001503861,0.0005731613,0.0003006471,0.00001038618],"category_scores_gemma":[0.00002399046,0.0001849809,0.0002683099,0.0003609107,0.0001906245,0.000003032586,0.0001112138,0.0001766411,0.000002892162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003268702,"about_ca_system_score_gemma":0.0003107158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008780658,"about_ca_topic_score_gemma":0.000005697762,"domain_scores_codex":[0.9982986,0.00008862674,0.0006570285,0.0005516141,0.0001456868,0.0002583783],"domain_scores_gemma":[0.999097,0.00001365764,0.0003309695,0.0004609612,0.00002617523,0.00007115977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005784186,0.00003644244,0.0001341353,0.000311719,0.0000240115,6.71634e-7,0.00001145798,0.000001382846,0.00004513548,0.00002915697,0.0002549807,0.9991452],"study_design_scores_gemma":[0.0001293933,0.0001256435,0.000009157013,0.0007008242,0.0000587906,0.000003597805,0.00002669696,0.00002880014,0.00006358008,0.00007617418,0.9985826,0.0001947378],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005565809,0.9836165,0.01438396,0.000003534514,0.0006170125,0.0004971576,0.00004466785,0.000005409826,0.0007760508],"genre_scores_gemma":[0.00027017,0.9911935,0.007815413,0.00007799896,0.0001614382,0.00009812556,0.0000615551,0.00002200238,0.0002997568],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9989504,"threshold_uncertainty_score":0.7543301,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0552691643263784,"score_gpt":0.3911305341832428,"score_spread":0.3358613698568644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}