{"id":"W1994966130","doi":"10.1097/00126334-200204010-00007","title":"Higher Rate of Toxicity With No Increased Efficacy When Hydroxyurea Is Added to a Regimen of Stavudine Plus Didanosine and Nevirapine in Primary HIV Infection","year":2002,"lang":"en","type":"article","venue":"JAIDS Journal of Acquired Immune Deficiency Syndromes","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver; University of British Columbia","funders":"","keywords":"Didanosine; Nevirapine; Stavudine; Regimen; Hydroxycarbamide; Medicine; Adverse effect; Internal medicine; Gastroenterology; Chemotherapy; Viral load; Human immunodeficiency virus (HIV); Immunology; Viral disease; Sida; Zidovudine; Antiretroviral therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001429172,0.0001795946,0.0006878502,0.0002303824,0.0002723552,0.0003930471,0.0001529033,0.0003192727,0.001177987],"category_scores_gemma":[0.004647604,0.0001472195,0.0004971396,0.0002237848,0.0002542255,0.0001727303,0.0001667559,0.0004553656,0.000098215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003318527,"about_ca_system_score_gemma":0.0002020603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000438155,"about_ca_topic_score_gemma":0.0009400877,"domain_scores_codex":[0.998457,0.0009293111,0.0001205242,0.0001028324,0.000284759,0.0001056008],"domain_scores_gemma":[0.9957153,0.001970179,0.00125512,0.0002382572,0.0002496426,0.0005714973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.04982052,0.004400696,0.8020725,0.0003733586,0.0008502381,0.005048455,0.0005606851,0.0006612359,0.03351828,0.0001181846,0.0004164125,0.1021594],"study_design_scores_gemma":[0.001263701,0.05057994,0.9347325,0.00003257147,0.0003786161,0.005672072,0.0001424138,0.0009411399,0.005510058,0.00008291306,0.000648607,0.00001544838],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994085,0.0002482059,0.00005547531,0.00001493039,0.000004975239,0.00002077148,0.00001110156,0.000003569232,0.0002324301],"genre_scores_gemma":[0.9996846,0.00007102669,0.00007162336,0.00003166903,0.00001267463,0.000006515423,0.00001948923,7.613172e-7,0.0001016393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001429172,"threshold_uncertainty_score":0.007558286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01544228131039682,"score_gpt":0.2335817839507989,"score_spread":0.2181395026404021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}