{"id":"W1995013829","doi":"10.1097/fpc.0b013e32835d9b0b","title":"The LCS6 polymorphism in the binding site of let-7 microRNA to the KRAS 3′-untranslated region","year":2013,"lang":"en","type":"article","venue":"Pharmacogenetics and Genomics","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saint Paul University","funders":"","keywords":"KRAS; Colorectal cancer; Internal medicine; Genotype; Medicine; Oncology; Allele; Pharmacogenetics; Chemotherapy; Single-nucleotide polymorphism; Cancer; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001431722,0.0001094143,0.0001364169,0.00003237812,0.0002011225,0.00003236726,0.0001045573,0.00002312783,0.000007973592],"category_scores_gemma":[0.000006647065,0.00005049938,0.00004550887,0.0001429625,0.00008233031,0.00001094661,0.00004582646,0.00009742859,0.00001251586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000285177,"about_ca_system_score_gemma":0.00002486701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003375824,"about_ca_topic_score_gemma":0.0001607509,"domain_scores_codex":[0.9993625,0.00003578742,0.0001859358,0.0001285533,0.00009794104,0.0001892432],"domain_scores_gemma":[0.9996128,0.00009296411,0.00005054451,0.0001558663,0.00004224321,0.00004555288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008635005,0.0002579173,0.05288027,0.00007616075,0.0007433,0.00004784458,0.03148404,0.0001587786,0.5658426,0.0001581495,0.01328943,0.334198],"study_design_scores_gemma":[0.004818759,0.0008657047,0.2644859,0.00008439294,0.0007553736,0.0001693199,0.002472338,0.002005898,0.04800621,0.0003800988,0.6755487,0.0004073071],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9649271,0.01279496,0.0000155233,0.021123,0.0001119401,0.0007250604,0.00001475488,0.000003979872,0.0002836343],"genre_scores_gemma":[0.9887481,0.009707458,0.00005693371,0.001172854,0.00009300452,0.00004850563,0.000004087929,0.00001099044,0.0001580543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6622593,"threshold_uncertainty_score":0.2059305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02180236331550997,"score_gpt":0.2787751533284489,"score_spread":0.2569727900129389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}