{"id":"W1995023702","doi":"10.1053/j.gastro.2012.03.010","title":"Genotype–Phenotype Relationships in Hepatocellular Carcinoma: p53 Inactivation Promotes Tumors With Stem Cell Features","year":2012,"lang":"en","type":"letter","venue":"Gastroenterology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institut National Du Cancer; Labex Immuno-Oncology; Université Paris Descartes; CNIB","keywords":"Hepatocellular carcinoma; Phenotype; Cancer research; Stem cell; Genotype; Biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001958412,0.0003251518,0.0005016981,0.001496338,0.0001571598,0.0003014188,0.0002272966,0.0007098399,0.03760708],"category_scores_gemma":[0.0004169821,0.0001226856,0.000581141,0.001247802,0.0001589349,0.0002776008,0.0002642436,0.0005332019,0.004100422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003166998,"about_ca_system_score_gemma":0.0001443218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009338742,"about_ca_topic_score_gemma":0.002338714,"domain_scores_codex":[0.999864,0.00002080114,0.000009423657,0.00002209481,0.00006209243,0.00002159905],"domain_scores_gemma":[0.9997059,0.0001184196,0.00007592959,0.00001430949,0.00005336036,0.00003209305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001803382,0.0003180763,0.01722009,0.006239722,0.0005555599,0.003634153,0.0001360411,0.0004170743,0.1464233,0.003856343,0.4681692,0.3512271],"study_design_scores_gemma":[0.0002993666,0.001789466,0.2122715,0.001291701,0.0008245819,0.02054755,0.0002202112,0.0007479207,0.07003967,0.008030296,0.6837959,0.0001419484],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1388669,0.6661149,0.009663209,0.04733836,0.01068862,0.0003981283,0.04300966,0.002113011,0.08180709],"genre_scores_gemma":[0.431003,0.3828717,0.005234784,0.01592344,0.006897971,0.0003969084,0.03068824,0.0005082567,0.1264757],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.03760708,"threshold_uncertainty_score":0.1258082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01870782544261049,"score_gpt":0.2078657055659852,"score_spread":0.1891578801233748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}