{"id":"W1995036572","doi":"10.1021/bi049404k","title":"Metal-Selective DNA-Binding Response of <i>Escherichia coli</i> NikR","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Divalent; Escherichia coli; Chemistry; Operon; DNA; Nickel; Repressor; Metal; Binding site; Biochemistry; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002139873,0.0004281005,0.0004155146,0.0001460322,0.0001418251,0.0003588423,0.0003416158,0.0003215423,0.001527286],"category_scores_gemma":[0.0003669207,0.000216681,0.0002522281,0.0001081466,0.0002354137,0.000156857,0.0002715639,0.0005111219,0.0009517043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005276375,"about_ca_system_score_gemma":0.0001490113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009378408,"about_ca_topic_score_gemma":0.001047044,"domain_scores_codex":[0.9994617,0.0001005116,0.00003619796,0.0001202152,0.0001685163,0.0001128299],"domain_scores_gemma":[0.9997669,0.00005700901,0.00005105802,0.00003074948,0.00005114672,0.0000431823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003222356,0.000009237217,0.00006388321,0.00002006463,0.000001251469,0.000009593331,0.000006806428,0.00001262225,0.9995034,0.00001387709,0.00002669578,0.000300409],"study_design_scores_gemma":[0.000002663716,0.00005027287,0.001245429,0.000001829686,0.000001872811,0.00007429288,0.0000140132,0.0002969879,0.9978532,0.000007149239,0.0004490118,0.000003284536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919173,0.0006675198,0.003952469,0.0002066241,0.00003358521,0.00003223362,0.0004339622,0.000318166,0.002438063],"genre_scores_gemma":[0.9907748,0.0002899617,0.004616366,0.0001923106,0.00001247753,0.00003146927,0.0008842847,0.00008968214,0.003108698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001527286,"threshold_uncertainty_score":0.005109251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00605261652655831,"score_gpt":0.2262944716237761,"score_spread":0.2202418550972178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}