{"id":"W1995038234","doi":"10.1038/cr.2007.114","title":"Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA","year":2007,"lang":"en","type":"review","venue":"Cell Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":207,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Biology; Proliferating cell nuclear antigen; DNA damage; DNA replication; Postreplication repair; DNA polymerase; DNA repair; Genome instability; Mutagenesis; DNA re-replication; Ubiquitin; Cell biology; DNA; Polymerase; Saccharomyces cerevisiae; Control of chromosome duplication; Genetics; Eukaryotic DNA replication; Mutation; Nucleotide excision repair; Yeast; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000515151,0.001181895,0.001416838,0.001165503,0.0003190089,0.0009175714,0.001272987,0.001172746,0.001614499],"category_scores_gemma":[0.0003850506,0.0004382358,0.0003551216,0.001742047,0.0008333315,0.001271298,0.0006148319,0.001543773,0.002544874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008741969,"about_ca_system_score_gemma":0.0007218042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006260459,"about_ca_topic_score_gemma":0.0008901067,"domain_scores_codex":[0.9998338,0.00001472034,0.00001990436,0.00004787149,0.00006410913,0.00001955141],"domain_scores_gemma":[0.9998316,0.00006245857,0.00003191398,0.00001368767,0.00004322531,0.00001707573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001293037,0.0000693068,0.0001329338,0.007935019,0.0000582076,0.0004736196,0.00005849758,0.0007385072,0.04234475,0.007003912,0.01241323,0.9286427],"study_design_scores_gemma":[0.00002446079,0.0001140577,0.0005405075,0.0005547992,0.000075,0.001728336,0.00004325051,0.0001603581,0.0354953,0.002701562,0.9585323,0.00002999718],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008241007,0.994099,0.002070352,0.0002325462,0.0005176857,0.00001391213,0.00002713416,0.000041222,0.002174068],"genre_scores_gemma":[0.002855533,0.9931697,0.001196008,0.0001913107,0.0001701359,0.00001848763,0.00006896194,0.000006908731,0.002323065],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001614499,"threshold_uncertainty_score":0.006342709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1810185142422434,"score_gpt":0.4243959084053585,"score_spread":0.2433773941631151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}