{"id":"W1995047633","doi":"10.1016/j.ejphar.2009.08.020","title":"Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer","year":2009,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"Associazione Italiana per la Ricerca sul Cancro; Pfizer","keywords":"Irinotecan; Oxaliplatin; Medicine; Colorectal cancer; Pharmacology; In vivo; Cancer; Vascular endothelial growth factor; Combination therapy; Cancer research; Internal medicine; Biology; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000480037,0.0001420106,0.0003838927,0.0002696399,0.00003168718,0.000007795187,0.00008968495,0.00002845229,0.0008332828],"category_scores_gemma":[0.00001324448,0.0001207646,0.00007836397,0.0001355053,0.00007159868,0.0000854166,0.00002372864,0.0003981412,0.00001468023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00019275,"about_ca_system_score_gemma":0.0001300351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001125688,"about_ca_topic_score_gemma":0.000008771462,"domain_scores_codex":[0.9987663,0.00032299,0.000437595,0.0001438129,0.00008843162,0.0002408557],"domain_scores_gemma":[0.9994315,0.00007140425,0.0002418896,0.00003423324,0.00006312098,0.0001578739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004160285,0.0008464335,0.03015367,0.000022051,0.0003356685,0.003488718,0.0008149142,0.0001108263,0.8122084,0.00002802583,0.02352038,0.1243106],"study_design_scores_gemma":[0.026117,0.01021203,0.812848,0.00008319262,0.00087553,0.002145683,0.00009866902,0.0002464782,0.1054575,0.00004365134,0.04158333,0.0002889191],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880637,0.002645752,0.00001314457,0.00546742,0.0006105383,0.0001616522,0.000004820167,0.00001094275,0.003022045],"genre_scores_gemma":[0.9957271,0.001014335,0.0003113429,0.002003892,0.0007578704,0.00000180088,0.000001797469,0.00001575292,0.0001660985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7826943,"threshold_uncertainty_score":0.9123862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01969729025367024,"score_gpt":0.3326786268966611,"score_spread":0.3129813366429908,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}