{"id":"W1995068068","doi":"10.1016/j.ccr.2014.01.021","title":"Mutant p53 in Cancer: New Functions and Therapeutic Opportunities","year":2014,"lang":"en","type":"review","venue":"Cancer Cell","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":1555,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Cancer Research UK; Wellcome Trust; Royal Society; Cancer Research Society","keywords":"Mutant; Cancer; Cancer research; Cancer cell; Biology; Computational biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006172457,0.0009607158,0.001354276,0.001823646,0.000260791,0.001038074,0.0009391799,0.001216656,0.002839295],"category_scores_gemma":[0.0007454921,0.0002812422,0.0004262851,0.001864009,0.0007199,0.001458975,0.000864766,0.002561992,0.00160443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006364629,"about_ca_system_score_gemma":0.0009329391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006468164,"about_ca_topic_score_gemma":0.001615112,"domain_scores_codex":[0.9998266,0.00002702482,0.0000234939,0.00003106695,0.00006952197,0.00002232323],"domain_scores_gemma":[0.9996899,0.0001375388,0.00004045311,0.00001050727,0.00008108699,0.00004062003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001142938,0.00006602325,0.0001649102,0.008731955,0.00006449531,0.0001968297,0.00003834644,0.0004886267,0.002059425,0.003861418,0.03867408,0.9455395],"study_design_scores_gemma":[0.00003115534,0.0000816501,0.0006101489,0.00179545,0.0001214423,0.001124776,0.00004541765,0.0001448239,0.000552158,0.002809667,0.9926622,0.0000211047],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008640956,0.9984227,0.0001644112,0.0003624081,0.0002218548,0.000003034017,0.00001602893,0.000008272537,0.0007149313],"genre_scores_gemma":[0.0006156689,0.9982917,0.0001744703,0.0002347698,0.0002646782,0.000003672963,0.00002478251,0.000001233486,0.0003890665],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002839295,"threshold_uncertainty_score":0.009498417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1272996133643841,"score_gpt":0.3470221038256088,"score_spread":0.2197224904612247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}