{"id":"W1995103418","doi":"10.1185/030079908x280725","title":"In vitro disintegration and dissolution studies of once-weekly copies of alendronate sodium tablets (70  mg) and in vivo implications","year":2008,"lang":"en","type":"article","venue":"Current Medical Research and Opinion","topic":"Bone health and treatments","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Alendronic acid; Immediate release; Dissolution; Pharmacology; Dosage form; Bisphosphonate; Internal medicine; Chemistry; Osteoporosis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005324413,0.00007520364,0.0002794386,0.0002205785,0.00007658316,0.000002552318,0.00002910286,0.00006643008,0.000006794684],"category_scores_gemma":[0.000897491,0.00005554961,0.00001255771,0.0002281763,0.0006562528,0.00008753023,0.00006066144,0.000258433,4.312548e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005986096,"about_ca_system_score_gemma":0.0002226971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003288949,"about_ca_topic_score_gemma":0.0001827291,"domain_scores_codex":[0.9987303,0.00009354542,0.0003140568,0.0001927155,0.0004301616,0.0002392006],"domain_scores_gemma":[0.9991578,0.0003223531,0.00004841106,0.00009056091,0.0001406198,0.0002401894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003600256,0.002947273,0.6744241,0.004594756,0.00008267666,0.00003537896,0.004471035,1.842314e-7,0.01396715,0.002456211,0.005059147,0.2883619],"study_design_scores_gemma":[0.005506448,0.001050137,0.9803081,0.001788529,0.00001031863,0.0000574616,0.0005910898,0.0006463208,0.005171585,0.001676784,0.003103816,0.00008944095],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9679663,0.02523811,0.00001985497,0.006195554,0.00008799611,0.0004091327,0.00002683045,0.000003685441,0.00005249942],"genre_scores_gemma":[0.902676,0.09712517,0.00003926728,0.00001183959,0.00002507218,0.00004670398,0.00003645993,0.000003494292,0.00003595899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.305884,"threshold_uncertainty_score":0.2417991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1915947261061282,"score_gpt":0.4885672652288719,"score_spread":0.2969725391227437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}