{"id":"W1995118129","doi":"10.1038/cddis.2014.58","title":"Glycogen synthase kinase 3β represses MYOGENIN function in alveolar rhabdomyosarcoma","year":2014,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Myogenin; Myogenesis; GSK-3; Alveolar rhabdomyosarcoma; Biology; PAX3; Molecular biology; Rhabdomyosarcoma; Glycogen synthase; Myogenic regulatory factors; Myocyte; Cell biology; Kinase; Phosphorylation; Biochemistry; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009484082,0.000144603,0.0001128762,0.00004065338,0.00008031454,0.00001496518,0.00008515963,0.00009454824,0.00004555592],"category_scores_gemma":[0.0001818354,0.0001402316,0.00006761274,0.00004644437,0.00006468364,0.000006343852,0.00007289992,0.00005928094,0.00001477944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003276461,"about_ca_system_score_gemma":0.00005184444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003121662,"about_ca_topic_score_gemma":0.00001142771,"domain_scores_codex":[0.9990959,0.00009086829,0.0001299382,0.0004068376,0.00005706773,0.0002193491],"domain_scores_gemma":[0.9992769,0.00001950434,0.00003820992,0.0003270758,0.00002213198,0.0003162042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00659897,0.001003428,0.2495755,0.0003281246,0.00005735525,0.00006254787,0.00006481294,0.0003613719,0.720607,0.001122814,0.005472578,0.01474548],"study_design_scores_gemma":[0.01028281,0.001748929,0.723829,0.00008484667,0.0003708854,0.000009823618,0.0002624682,0.002215094,0.1570556,0.01823193,0.08410217,0.001806468],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926671,0.004141335,0.0007319434,0.00007599727,0.00007774533,0.0001301275,0.00001801063,0.00001415173,0.002143606],"genre_scores_gemma":[0.9983549,0.0002233635,0.00006146132,0.0008150995,0.0001061252,0.00003537572,0.0002024736,0.00001353782,0.0001877029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5635514,"threshold_uncertainty_score":0.5718478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005552575763065686,"score_gpt":0.2100271978254084,"score_spread":0.2044746220623427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}