{"id":"W1995153987","doi":"10.1089/088922200309575","title":"Cell-Dependent Mechanisms Restrict the HIV Type 1 Coreceptor Activity of US28, a Chemokine Receptor Homolog Encoded by Human Cytomegalovirus","year":2000,"lang":"en","type":"article","venue":"AIDS Research and Human Retroviruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Neurological Disorders and Stroke; Elizabeth Glaser Pediatric AIDS Foundation; Vetenskapsrådet; National Institutes of Health; G. Harold and Leila Y. Mathers Foundation","keywords":"Biology; Virology; Chemokine receptor; CXCR4; Viral entry; Tropism; Cell type; Viral life cycle; Human cytomegalovirus; Cell culture; Virus; Cell; Chemokine; Receptor; Chemokine receptor CCR5; Cell biology; Viral replication; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001139372,0.0003485406,0.0002666021,0.0002513035,0.0001661254,0.0004251342,0.0002205168,0.0002737788,0.0009223959],"category_scores_gemma":[0.000189525,0.0001894072,0.0004047131,0.000130311,0.0002538677,0.0003085763,0.0003142402,0.0004256524,0.0004596502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000362034,"about_ca_system_score_gemma":0.0002407978,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009222579,"about_ca_topic_score_gemma":0.001260818,"domain_scores_codex":[0.9997767,0.00003544588,0.00001484602,0.00003244548,0.00007849438,0.00006206096],"domain_scores_gemma":[0.9998413,0.0000477743,0.00002682488,0.00003928645,0.00002553185,0.00001925957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002348833,0.00001252147,0.0001843192,0.00001984883,0.00000277954,0.00003094835,0.00001460479,0.0000189626,0.9988326,0.0001790819,0.00002268766,0.0006581951],"study_design_scores_gemma":[0.000007169646,0.0001434232,0.006980168,0.00000696238,0.00000827423,0.0003175509,0.00003480765,0.0008993794,0.9885244,0.00008141349,0.002991882,0.000004641316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912485,0.003694718,0.003006134,0.00005304697,0.00002147359,0.00003959901,0.0001968488,0.00005738754,0.001682175],"genre_scores_gemma":[0.9940422,0.001221408,0.001701506,0.00003805982,0.00001169361,0.00004534109,0.0005341136,0.0000167808,0.002388865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009223959,"threshold_uncertainty_score":0.003085673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03944267055037635,"score_gpt":0.3192134621095097,"score_spread":0.2797707915591334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}