{"id":"W1995153987","doi":"10.1089/088922200309575","title":"Cell-Dependent Mechanisms Restrict the HIV Type 1 Coreceptor Activity of US28, a Chemokine Receptor Homolog Encoded by Human Cytomegalovirus","year":2000,"lang":"en","type":"article","venue":"AIDS Research and Human Retroviruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Neurological Disorders and Stroke; Elizabeth Glaser Pediatric AIDS Foundation; Vetenskapsrådet; National Institutes of Health; G. Harold and Leila Y. Mathers Foundation","keywords":"Biology; Virology; Chemokine receptor; CXCR4; Viral entry; Tropism; Cell type; Viral life cycle; Human cytomegalovirus; Cell culture; Virus; Cell; Chemokine; Receptor; Chemokine receptor CCR5; Cell biology; Viral replication; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00119024,0.0003176221,0.0004979006,0.0003064165,0.001285844,0.00008981521,0.0007000754,0.0003175597,0.0114675],"category_scores_gemma":[0.0001442515,0.0002203004,0.0001123476,0.0005064688,0.00144583,0.0001632117,0.0002668335,0.001098679,0.002245254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001601392,"about_ca_system_score_gemma":0.0001677254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002275091,"about_ca_topic_score_gemma":0.0001301217,"domain_scores_codex":[0.9965256,0.0009272443,0.0003813447,0.0006447153,0.0003839871,0.001137124],"domain_scores_gemma":[0.9982124,0.0005113689,0.0001119238,0.0007218944,0.0002759263,0.0001664919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001053171,0.000959034,0.007474708,0.0000396613,0.000253148,0.00001625887,0.0002572481,2.113304e-7,0.9115325,0.0008832694,0.07336795,0.004162838],"study_design_scores_gemma":[0.003272645,0.00842383,0.007897183,0.00003566804,0.00003850705,0.00001841492,0.0002641501,2.213152e-7,0.9311858,0.0008251267,0.0477396,0.000298863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991051,0.002124824,0.000009194495,0.000155198,0.00006747232,0.0007089744,0.0007375843,0.00006253715,0.005083191],"genre_scores_gemma":[0.9572822,0.001107993,0.00005001117,0.00003354294,0.00004593173,0.0001038316,0.0003907937,0.00003788896,0.04094779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0358646,"threshold_uncertainty_score":0.9985316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03944267055037635,"score_gpt":0.3192134621095097,"score_spread":0.2797707915591334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}