{"id":"W1995191891","doi":"10.1101/pdb.prot080358","title":"Genetic Manipulation of Autophagy in the <i>Drosophila</i> Ovary","year":2014,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Germline; Biology; Gene knockdown; Mutant; Autophagy; Somatic cell; Gene; Genetics; Drosophila (subgenus); RNA interference; Drosophila melanogaster; Germline mutation; Genetic screen; Genetic analysis; Mutation; Cell biology; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002816521,0.0001038059,0.0001088973,0.00003500712,0.00002696534,0.00001538428,0.0002330851,0.00007491827,0.000003759846],"category_scores_gemma":[0.00005098665,0.00009023853,0.00005071127,0.00008927193,0.00002566457,0.000002194588,0.00005332777,0.00007139478,0.000003130635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006505784,"about_ca_system_score_gemma":0.00001886127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001218856,"about_ca_topic_score_gemma":0.00000634743,"domain_scores_codex":[0.9992533,0.00005294524,0.0002189649,0.0001934867,0.0001191707,0.0001621309],"domain_scores_gemma":[0.9994651,0.00001451641,0.00005697608,0.0004098763,0.00002712897,0.00002641848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002045977,0.00004679204,0.007945813,0.00008727809,0.000006842004,0.000001457632,0.00002151703,0.003011182,0.9862704,0.002183957,0.000048718,0.0003555523],"study_design_scores_gemma":[0.0006248238,0.0002107559,0.3567541,0.0000618876,0.000006484922,0.000001465886,0.000003548253,0.002079756,0.613283,0.00006006034,0.02675641,0.0001577033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9496313,0.00025753,0.02719712,0.00008297977,0.00007410863,0.02198611,0.000002778749,0.00002393868,0.0007441596],"genre_scores_gemma":[0.9879721,0.000004857885,0.001707893,0.00009898389,0.0001670848,0.01001645,8.324261e-7,0.0000173549,0.00001442608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3729874,"threshold_uncertainty_score":0.367982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01263124887878304,"score_gpt":0.2912364863026034,"score_spread":0.2786052374238204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}