{"id":"W1995259631","doi":"10.1038/nbt.2261","title":"Should preclinical studies be registered?","year":2012,"lang":"en","type":"letter","venue":"Nature Biotechnology","topic":"Animal testing and alternatives","field":"Veterinary","cited_by":96,"is_retracted":false,"has_abstract":false,"ca_institutions":"NeuroDevNet; University of British Columbia Hospital; University of British Columbia; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Computational biology; Medicine; Pharmacology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.02678612,0.001476725,0.003011072,0.001404157,0.00919246,0.01164588,0.005760083,0.269678,0.0168409],"category_scores_gemma":[0.06197668,0.00262614,0.003853754,0.001644889,0.006241827,0.007421896,0.004773648,0.09120245,0.01267193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.008022681,"about_ca_system_score_gemma":0.02399291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01021474,"about_ca_topic_score_gemma":0.03703436,"domain_scores_codex":[0.9759546,0.005114472,0.003183313,0.00302565,0.008268359,0.00445367],"domain_scores_gemma":[0.9591504,0.02183823,0.003881602,0.001620695,0.006364622,0.007144432],"domain_codex":null,"domain_gemma":"reproducibility","domain_candidate":"reproducibility","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002872915,0.0001704226,0.001067437,0.0001909652,0.00005881112,0.002837823,0.0002218852,0.0001548625,0.001104982,0.01367383,0.9658993,0.01433244],"study_design_scores_gemma":[0.0002628074,0.0002441969,0.001873432,0.0005451675,0.0001110093,0.00169897,0.0003237411,0.0006050381,0.0006438988,0.01462037,0.9789335,0.0001378885],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001230087,0.00179992,0.0006797258,0.9579388,0.01990452,0.0001254321,0.0001813329,0.0001460303,0.01799418],"genre_scores_gemma":[0.003260139,0.0006446856,0.0005329791,0.9614912,0.009726722,0.00009173177,0.00005493206,0.00004565094,0.02415192],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.9732139,"threshold_uncertainty_score":0.1416602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4669688666313941,"score_gpt":0.5047749897482955,"score_spread":0.03780612311690135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}