{"id":"W1995298140","doi":"10.1016/s1521-6616(03)00097-4","title":"The flotillins are integral membrane proteins in lipid rafts that contain TCR-associated signaling components: implications for T-cell activation","year":2003,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":false,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Aging; U.S. Public Health Service","keywords":"Lipid raft; T-cell receptor; Cell biology; Raft; CD28; Signal transduction; Biology; T cell; CD3; Antigen; CD8; Chemistry; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004831716,0.0003881373,0.0002037898,0.000717922,0.0003293941,0.0008132868,0.0003855382,0.0009607308,0.0008020782],"category_scores_gemma":[0.0004372506,0.0001340598,0.0001377381,0.0002413996,0.0009687238,0.0008500787,0.0003411859,0.0008716077,0.0002469504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004592691,"about_ca_system_score_gemma":0.000188117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002694167,"about_ca_topic_score_gemma":0.0003041467,"domain_scores_codex":[0.9999247,0.00001007032,0.000005565054,0.00001090385,0.00002107464,0.0000277138],"domain_scores_gemma":[0.9998633,0.00003390701,0.00004345682,0.000005320216,0.00002207419,0.00003193978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001643704,0.00008603479,0.003920916,0.0004646395,0.00004079299,0.003679643,0.0002378752,0.0003235159,0.886606,0.02570823,0.002950059,0.0743386],"study_design_scores_gemma":[0.0002899469,0.001290979,0.03860592,0.0002437165,0.0001860057,0.03643635,0.0004429104,0.002058605,0.7615513,0.01932069,0.1394816,0.00009201167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7248728,0.2286147,0.01616996,0.01542117,0.0009801473,0.0001230071,0.000534109,0.0003795983,0.01290456],"genre_scores_gemma":[0.9470053,0.0413605,0.00403269,0.001150906,0.001119115,0.00003783112,0.0002568694,0.00003940032,0.004997405],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009607308,"threshold_uncertainty_score":0.003332257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04683265539695027,"score_gpt":0.3109987158234421,"score_spread":0.2641660604264918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}