{"id":"W1995315737","doi":"10.1371/journal.pone.0119954","title":"Actin Cytoskeleton Regulation of Epithelial Mesenchymal Transition in Metastatic Cancer Cells","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":161,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Cancer Society Research Institute; Cancer Research Society","keywords":"Cytochalasin D; Cadherin; RHOA; Vimentin; Cell biology; Actin cytoskeleton; Cytoskeleton; Epithelial–mesenchymal transition; Cytochalasin; Cancer cell; Biology; Actin; Adherens junction; RAC1; Cell; Chemistry; Signal transduction; Cancer; Metastasis; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004753514,0.0001621548,0.0001348052,0.0001819159,0.0002234061,0.0002258205,0.00006681406,0.0001454205,0.001112765],"category_scores_gemma":[0.00005853687,0.000124409,0.000162916,0.0001299954,0.00009551687,0.0001081995,0.0001459914,0.0003047824,0.0003879914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002596269,"about_ca_system_score_gemma":0.0001294089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008859932,"about_ca_topic_score_gemma":0.001529046,"domain_scores_codex":[0.9999249,0.00001317199,0.000005147306,0.00001401023,0.00002216035,0.00002065398],"domain_scores_gemma":[0.9999518,0.000005287636,0.00001185679,0.000004628706,0.0000141658,0.00001225334],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002416286,0.000007272725,0.0001197821,0.00001410563,0.000001250814,0.0000374944,0.000006823511,0.00001432596,0.9992521,0.00004760801,0.00003862756,0.0004362635],"study_design_scores_gemma":[0.0000113265,0.0001560719,0.01993107,0.00001010204,0.00001144779,0.000410701,0.0000534001,0.0009828964,0.9719325,0.00006815239,0.006426568,0.00000577907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855742,0.00529291,0.003600811,0.0001984751,0.00004165454,0.00004441335,0.0006425565,0.0001016107,0.0045033],"genre_scores_gemma":[0.9912103,0.0025183,0.001463004,0.00007197967,0.00001320873,0.0000472264,0.0007280273,0.00001168066,0.00393624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001112765,"threshold_uncertainty_score":0.003722548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08982834099681578,"score_gpt":0.2900902398701659,"score_spread":0.2002618988733501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}