{"id":"W1995346298","doi":"10.1111/j.1365-2958.2009.07020.x","title":"The permease gene<i>nagE2</i>is the key to<i>N</i>‐acetylglucosamine sensing and utilization in<i>Streptomyces coelicolor</i>and is subject to multi‐level control","year":2010,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Deutsche Forschungsgemeinschaft","keywords":"Permease; Streptomyces coelicolor; Biology; Actinorhodin; PEP group translocation; Biochemistry; Nutrient sensing; Mutant; Activator (genetics); Phosphoenolpyruvate carboxykinase; Phosphotransferase; Gene; Cell biology; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001010513,0.0006019928,0.0004387535,0.0001594784,0.0001709443,0.0005827114,0.0001798492,0.0002852502,0.0008685386],"category_scores_gemma":[0.000178583,0.0001707348,0.0002826015,0.0001506191,0.0003311517,0.0002511094,0.0003840187,0.000503124,0.0006047765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004555871,"about_ca_system_score_gemma":0.0001901559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001103592,"about_ca_topic_score_gemma":0.0009347074,"domain_scores_codex":[0.9998031,0.00002682058,0.00001343028,0.00005562131,0.00006422674,0.00003672265],"domain_scores_gemma":[0.9998549,0.00002169884,0.0000443128,0.00001974886,0.00001646822,0.00004287472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002751547,0.000004348049,0.0002513129,0.00001703821,0.000002370708,0.00002225811,0.000006404508,0.00002729916,0.9988201,0.00005446672,0.00002121918,0.0007455408],"study_design_scores_gemma":[0.00000681414,0.00008008101,0.01054902,0.000003937431,0.000009704742,0.000474034,0.00003116543,0.000877669,0.9846622,0.00007657147,0.003219101,0.000009632618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842507,0.002258619,0.009817353,0.0001834999,0.00004618354,0.00002597784,0.0007022197,0.0005708001,0.002144635],"genre_scores_gemma":[0.9917579,0.0005573833,0.003573702,0.00005850667,0.00001385611,0.00001775504,0.001243745,0.00006487974,0.002712227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001103592,"threshold_uncertainty_score":0.003305554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01706984581776917,"score_gpt":0.2552708135570375,"score_spread":0.2382009677392684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}