{"id":"W1995484601","doi":"10.1053/j.gastro.2004.11.058","title":"Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant","year":2005,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's Hospital of Eastern Ontario","funders":"","keywords":"Survivin; Cancer research; Mitotic catastrophe; Angiogenesis; Apoptosis; Carcinogenesis; Suicide gene; Biology; Genetic enhancement; Colorectal cancer; Cancer; Cancer cell; In vivo; Programmed cell death; Molecular biology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001767901,0.000340931,0.0003331669,0.0002881314,0.000221202,0.0002632401,0.0001692183,0.0003613218,0.0009822147],"category_scores_gemma":[0.0001255226,0.0001490356,0.0002960285,0.0002292473,0.000290575,0.0002690666,0.000172088,0.0007065298,0.0002475228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004176768,"about_ca_system_score_gemma":0.000374254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009481875,"about_ca_topic_score_gemma":0.000942268,"domain_scores_codex":[0.9998934,0.00001556907,0.00001166418,0.00001947134,0.00003154319,0.00002820732],"domain_scores_gemma":[0.9999559,0.000008350175,0.0000134238,0.000007525101,0.000005528131,0.000009255229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001469894,0.00003090246,0.00008532924,0.00003101237,0.000008392981,0.00007261903,0.00001909714,0.0001391349,0.9969029,0.0006795587,0.00007151021,0.001812549],"study_design_scores_gemma":[0.0000539499,0.0004288427,0.0006814449,0.000004597797,0.00002848591,0.0003570597,0.00001597365,0.001207471,0.9932584,0.0001028704,0.00385519,0.000005766407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863767,0.002393225,0.008139695,0.0002903698,0.0001283933,0.00008338902,0.0002609335,0.0001323786,0.002194816],"genre_scores_gemma":[0.9924972,0.001048632,0.003457249,0.00002934672,0.00001174955,0.00003563587,0.0002440161,0.00002453914,0.002651624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009822147,"threshold_uncertainty_score":0.003285885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01174974206986952,"score_gpt":0.2774023371879478,"score_spread":0.2656525951180783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}